Sökning: "cell of origin"

Visar resultat 1 - 5 av 507 avhandlingar innehållade orden cell of origin.

  1. 1. Cellular Origin and Development of Glioma

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nanna Lindberg; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; MEDICINE Morphology; cell biology; pathology; MEDICIN Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

    Sammanfattning : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. LÄS MER

  2. 2. Unique Solutions to Universal Problems Studies of the Archaeal Cell

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Erik A. Pelve; Uppsala universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Archaea; Cdv; Cell cycle; Cell division; Cell lysis; Crenarchaea; ESCRT-III; Flow cytometry; Microarray; Microscopy; Nitrosopumilus; SIRV2; Sulfolobus; Thaumarchaea; Transcription; VAP; Virus; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Archaea is one of the three domains of life and studies of archaeal biology are important for understanding of life in extreme environments, fundamental biogeochemical processes, the origin of life, the eukaryotic cell and their own, unique biology. This thesis presents four studies of the archaeal cell, using the extremophilic Sulfolobus and ocean living Nitrosopumilus as model systems. LÄS MER

  3. 3. Interplay Between Cell of Origin and Oncogenic Activation in Glioma

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Yiwen Jiang; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; PDGF; cell of origin; Sox5; glioma initiating cells; Oncology; Onkologi;

    Sammanfattning : Glioma is the most frequent primary tumor of the central nervous system. By using the RCAS/tv-a mouse glioma model, we have studied mechanisms controlling glioma development and the effect of cell of origin on these processes.SOX5 was identified as a brain tumor locus in a retroviral insertional mutagenesis screen of PDGF-B induced mouse gliomas. LÄS MER

  4. 4. Expression and localisation of somatostatin receptor subtype 2a in neuroendocrine cells and cells of neuroectodermal origin

    Detta är en avhandling från Göteborg

    Författare :Sayed Hossein Hashemi; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SSR2 a receptor; somatostatin; neuroendocrine tumours; tissue culture; immunocytochemistry; SH-SY5Y cells; CAD cell line; ependyma; tanycytes; neuronal differentiation; catecholaminergic markers; cholinergic markers; synaptic vesicle membrane proteins; intermediate filaments.;

    Sammanfattning : .... LÄS MER

  5. 5. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells Investigations in vitro and in Reactive Tissues in vivo

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jakob Karén; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

    Sammanfattning : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. LÄS MER