Sökning: "Glioblastoma GBM"
Visar resultat 1 - 5 av 54 avhandlingar innehållade orden Glioblastoma GBM.
1. New Molecular Approaches to Glioblastoma Therapy
Sammanfattning : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. LÄS MER
2. Tertiary lymphoid structures in glioblastoma : Discovery, Characterization and Therapeutic Induction
Sammanfattning : Glioblastoma (GBM) is an incurable brain cancer with a median survival of less than two years from diagnosis. The tumor microenvironment plays a major role in GBM progression through sustaining immunosuppression and poor lymphocytic infiltration. LÄS MER
3. A Novel Approach for Radiotherapy and Radiosurgery Treatment Planning Accounting for High-Grade Glioma Invasiveness into Normal Tissue
Sammanfattning : High-grade gliomas (HGGs) are a type of malignant brain cancer, which include glioblastomas (GBMs). In adults, GBM is the most common malignant primary brain cancer. Attempts to treat patients with GBMs have been conducted for over a century, but the prognosis has only marginally improved. LÄS MER
4. Modeling glioblastoma heterogeneity to decipher its biology
Sammanfattning : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. LÄS MER
5. Modeling glioblastoma growth patterns and their mechanistic origins
Sammanfattning : Glioblastoma (GBM) is the most common and aggressive primary brain cancer. GBM cells migrate away from the primary lesion and invade healthy brain tissue. The invading cells escape surgical resection, radiotherapy and develop resistance to chemotherapy. Consequently, despite treatment, recurrence is inevitable, and survival is only 14 months. LÄS MER
