Sökning: "Benign Prostatic Hyperplasia"

Visar resultat 21 - 25 av 27 avhandlingar innehållade orden Benign Prostatic Hyperplasia.

  1. 21. A functional genomics approach to study prostate disorders

    Författare :See-Tong Pang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prostate cancer; BPH; androgen; DNA microarray; gene expression; CGH; SKY; oxidative stress.;

    Sammanfattning : Benign prostate hyperplasia (BPH) and prostate cancer (PCa) are the two most common prostatic disorders in elderly man. Currently, the causes of both diseases are still not clear. However, androgen is a well recognized risk factor for both diseases. LÄS MER

  3. 22. Molecular endocrinology of target enzymes in androgen metabolism : implications for prostate cancer

    Författare :Torbjörn Söderström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Genes that are responsible for variations in drug and hormonal responses are sometimes also associated with the pathophysiology of diseases. Understanding the aetiology of a disease is often essential for the design of effective drugs. Androgens are implicated in the development of prostate cancer and benign prostate hyperplasia (BPI]). LÄS MER

  4. 23. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

    Författare :Charlotte Becker; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. LÄS MER

  5. 24. Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer

    Författare :Anson Ku; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3. LÄS MER

  7. 25. Inguinal Hernia after Urologic Surgery in Males with Special Reference to Radical Retropubic Prostatectomy. A Clinical, Epidemiological and Methodological Study

    Författare :Johan Stranne; Göteborgs universitet; []
    Nyckelord :Prostate cancer; inguinal hernia; radical retropubic prostatectomy; Complication;

    Sammanfattning : Background and aims: In 1996 the first report indicating that inguinal hernia (IH) was a complication to radical retropubic prostatectomy (RRP) was published. The main aims of this thesis were to further establish this relation, to establish the background incidence of IH in men not subjected to surgery, to identify risk factors for postoperative IH occurrence and to investigate whether postoperative IH is a complication also after other types of surgery performed through a lower midline incision. LÄS MER