Sökning: "Batch Processes"

Visar resultat 31 - 35 av 141 avhandlingar innehållade orden Batch Processes.

1. 31. Chemometric methods for analysis of spectroscopic data from batch process monitoring

   Författare :Erik Furusjö; KTH; []
   Nyckelord :in situ spectroscopy; reaction monitoring; organic synthesis; solubility; crystallization; multivariate calibration; curve resolution; kinetic model; reaction rate constant; activation energy; target testing; bootstrap;

   Sammanfattning : Understanding of a process is essential for processdevelopment, optimisation and scale-up. In situ spectroscopy isan attractive measurement technique that can increase processunderstanding, since samples need not be retrieved from theprocess mixture. LÄS MER

3. 32. Cellular Processes and Mechanisms in Saccharomyces cerevisiae Influencing Anaerobic Xylose Fermentation

   Författare :Basti Bergdahl; Teknisk mikrobiologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; Bioethanol; Xylose metabolism; Metabolomics; Regulation; Protein folding; Microbial growth;

   Sammanfattning : In 2009 the EU approved two directives as a first initiative towards reducing greenhouse gas emissions and becoming independent of fossil fuels: the Renewable Energy Directive and the Fuel Quality Directive. As a result, the demand for biofuels will increase enormously over the next decade, both nationally and in the entire EU. LÄS MER

4. 33. Tools for the development of intensified perfusion processes for mammalian cell culture

   Författare :Hubert Schwarz; Véronique Chotteau; Mark Smales; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Recombinant protein biomanufacturing; Perfusion process; Integrated continuous bioprocessing; Monoclonal antibody; Erythropoietin; Chinese Hamster Ovary cells; Human Embryonic Kidney cells; Perfusion medium optimization; Cell specific perfusion rate; Raman spectroscopy; N-glycosylation; Microbioreactors; Design of Experiments; Biotechnology; Bioteknologi;

   Sammanfattning : Recombinant protein therapeutics have become an indispensable part of modern medicine to treat a wide variety of diseases. Their manufacture is mostly based on mammalian cells with fed-batch production bioreactors and downstream batch purification unit operations. LÄS MER

5. 34. Design and Control of Integrated Continuous Processes for the Purification of Biopharmaceuticals

   Författare :Joaquin Gomis Fons; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Integrated Continuous Biomanufacturing; Downstream Processing; Process Design and Optimization; Process Control; Biopharmaceuticals;

   Sammanfattning : The production of biopharmaceuticals so far has been based on batch processes that are robust and well-known, but very inefficient and inflexible, causing the products to be very expensive and process development to be slow and costly. The production of biopharmaceuticals is thus changing towards integrated continuous biomanufacturing (ICB) in order to reduce costs and increase flexibility in a constantly changing market. LÄS MER

7. 35. Protein Folding Activity of the Ribosome and Its Implication in Prion Processes

   Författare :Yanhong Pang; Suparna Sanyal; Patricia L. Clark; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Protein folding; Prion disease; Antiprion drug; Competitive inhibition; PFAR; Amyloid; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : How the linear protein chains fold into their three-dimensional active conformation is one of the remaining puzzles of modern science. Other than molecular chaperones, ribosome - the cellular protein synthesis machinery, has also been implicated in protein folding. LÄS MER