Sökning: "B vitamin"

Visar resultat 21 - 25 av 80 avhandlingar innehållade orden B vitamin.

  1. 21. Nuclear hormone receptor signaling in the developing CNS : studies on the retinoid receptors RAR and RXR, and the orphan receptors NURR1, NOR1 and NGFI-B

    Författare :Ludmila Solomin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The nuclear hormone receptor superfamily comprises more than sixty members, including receptors for steroids, thyroid hormone, vitamin D and retinoids. Many nuclear receptors function as ligand-induced transcription factors that upregulate expression of specific target genes. LÄS MER

  3. 22. Effects of 1,25-dihydroxyvitamin D3 and growth hormone on osteoblast-like cells

    Författare :Orlando Morales; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Vitamin D3; Growth Hormone; Osteoblasts; signal transduction;

    Sammanfattning : Bone remodeling, which occurs throughout life in both cancellous and cortical bone, involves mainly the osteoblasts and osteoclasts. The osteoblast is responsible for the production of matrix, which later becomes mineralized. The osteoclast is a large, multinuclear cell, which is responsible for bone resorption. LÄS MER

  4. 23. Immunomodulation of collagen-induced arthritis

    Författare :Lars Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :autoimmunity; arthritis; collagen type II; immunomodulation; vitamin D; parasite;

    Sammanfattning : Collagen-induced arthritis (CIA) is an experimental autoimmune disease sharing many features with human rheumatoid arthritis (RA). CIA development is dependent on T-cells but anti-collagen type II (anti-CII) antibody production by B-cells is also important. LÄS MER

  5. 24. On retinoid receptors, Nurr1 and related transcription factors in the CNS

    Författare :Rolf H Zetterström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nurr1; NGFI-B; Nor1; RAR; RXR; CRBP; CRABP; substantia nigra; basal ganglia; dopamine; orphan receptor; vitamin A; retinoic acid; transcription factor;

    Sammanfattning : It has long been known that retinoids (vitamin A derivatives) are required for normal development and growth; in excess however metabolites such as all-trans retinoic acid are potent teratogens. Retinoids exert their effects through transcription factors known as the retinoic acid receptors (RARam -ß and -y) and retinoid X receptors (RXRa, -ß and -y). LÄS MER

  7. 25. The impact of lifestyles on the occurrence of dementia

    Författare :Hui-Xin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alzheimer s disease; dementia; elderly; emotional support; folate; incidence; integration; intellectual activity; lifestyle; mental activity; physical activity; prevalence; productive activity; smoking; social activity; social network; risk factor; and vitamin B12.;

    Sammanfattning : This thesis explored the impact of different lifestyles in late life on the occurrence of Alzheimer's disease (AD) or dementia. Smoking, vitamin B12 and folate in relation to AD have been extensively studied, but the results are inconsistent. Research concerning the association between dementia and social network or social activities is scarce. LÄS MER