Sökning: "RXR"

Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet RXR.

  1. 1. Some aspects of nuclear receptor function in the CNS : novel roles of Nurr1 and RXR in developing and mature neurons

    Författare :Åsa Wallén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The nuclear receptor superfamily comprises the receptors for steroid hormones, thyroid hormone, vitamin D and retinoids. The family also includes a number of receptors that lack identified ligands, and are therefore referred to as orphan receptors. LÄS MER

  3. 2. Nuclear hormone receptor signaling in the developing CNS : studies on the retinoid receptors RAR and RXR, and the orphan receptors NURR1, NOR1 and NGFI-B

    Författare :Ludmila Solomin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The nuclear hormone receptor superfamily comprises more than sixty members, including receptors for steroids, thyroid hormone, vitamin D and retinoids. Many nuclear receptors function as ligand-induced transcription factors that upregulate expression of specific target genes. LÄS MER

  4. 3. Transcriptional regulation by the thyroid hormone receptor and its viral counterpart : the P75gag-V-erbA oncoprotein

    Författare :Gunilla Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Transcriptional regulation; thyroid hormone; TR; P75gag-v-erbA; repression; Avian erythroblastosis virus; response elements; RXR; retinoids.;

    Sammanfattning : Thyroid hormone binds to specific DNA binding receptors (TRs) in the cell nucleus and thus regulates transcription during development and in some pathological disorders. The gene of the viral TR homologue, v-erbA, is one of two oncogenes encoded in the genome of avian erythroblastosis virus (AEV). LÄS MER

  5. 4. Regulation of gene transcription by the thyroid hormone receptors

    Författare :Maria Nygård; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thyroid hormone receptors; T3; cell differentiation; gene regulation; E2F-1; Necdin; TRH; nTRE; RXR; NCoR; XAP-2;

    Sammanfattning : Thyroid hormone (TH) has important effects on postnatal development as well as on adult metabolic homeostasis. TH meditates its effects through different isoforms of the thyroid hormone receptors (TRs) encoded by the TRalpha and TRbeta genes, respectively. TRs belong to the nuclear hormone receptor superfamily. LÄS MER

  7. 5. Retinoids and vitamin D in skin and parathyroid glands

    Författare :Liu Wei; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; all-trans retinoic acid 9-cis retinoic acid vitamin A. vitamin D. CRBP. CRABP. RAR. RXR. parathyroid hormone. calcium receptor; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Vitamin D3 (VitD3) and retinoids are important factors involved in differentiation and proliferation in many cell systems. Their effects in skin, where retinoids and vitamin D are known to be crucially involved in keratinocyte differentiation and function,, and in the parathyroid, the overall regulatory organ in calcium homeostasis were studied. LÄS MER