Sökning: "Amino Acids biosynthesis"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Amino Acids biosynthesis.

  1. 1. Biosynthesis and physiological functions of N-acyl amino acids

    Författare :Dominik Paweł Waluk; Mary C. Hunt; David Merkler; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molekylärgenetik; Molecular Genetics;

    Sammanfattning : N-acyl amino acids are lipid signalling molecules that have recently been identified in biological systems. These lipids are structurally related to the endocannabinoids, although they do not activate cannabinoid receptors. LÄS MER

  3. 2. Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding

    Författare :Britt-Marie Iresjö; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein synthesis; Translation initiation; amino acids; Snat 2; MHC2A; IGF-I;

    Sammanfattning : Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. LÄS MER

  4. 3. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism : Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

    Författare :Kerstin Lundell; Kjell Wikvall; Ronnie Hansson; Stefan Alexson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Sammanfattning : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. LÄS MER

  5. 4. Design and Synthesis of Potential Aminoacyl-tRNA Synthetase Inhibitors

    Författare :Itedale Namro Redwan; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aminoacyl tRNA synthetases; Aminoacyl-AMP; Bioisosteres; Amino Acids; Solution-Phase; Protective Groups; Solid-Phase Chemistry; Molecular Modelling; Biological Evaluation;

    Sammanfattning : Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes present in all living organisms, their catalytic activity is involved in the translation of the genetic code into functional proteins and they are potential targets for anti-infective agents. The first step in the biosynthetic pathway catalysed by aaRSs consists of activation of the corresponding amino acid by the reaction with ATP to form an aminoacyl-adenylate (aa-AMP), the key intermediate in the biosynthesis of proteins. LÄS MER

  7. 5. Cell wall biosynthesis in the pathogenic oomycete Saprolegnia parasitica

    Författare :Elzbieta Rzeszutek; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cellulose biosynthesis; chitin biosynthesis; cellulose synthase genes; chitin synthase genes; oomycetes; Saprolegnia parasitica; Biotechnology; Bioteknologi;

    Sammanfattning : The oomycete Saprolegnia parasitica is a fungus-like microorganism responsible for the fish disease saprolegniosis, which leads to important economic losses in aquaculture. Currently, there is no efficient method to control the infection and therefore methods for disease management are urgently needed. LÄS MER