Sökning: "[alpha][beta] T cells"

Visar resultat 16 - 20 av 23 avhandlingar innehållade orden [alpha][beta] T cells.

  1. 16. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

    Författare :Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

    Sammanfattning : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). LÄS MER

  3. 17. Laminin of platelets and leukocytes : molecular characterization, integrin receptors and functional roles

    Författare :Tarekegn Geberhiwot; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Laminins are multifunctional, multidomain glycoproteins found predominantly in basement membranes. They are [alpha]/[beta]/[gamma] heterotrimers assembled from known chains. To date, twelve cell- and tissue-specific laminin isoforms have been reported laminins play at least two essential roles. LÄS MER

  4. 18. Regulation of tubulin heterodimer partitioning during interphase and mitosis

    Författare :Per Holmfeldt; Martin Gullberg; Pontus Aspenström; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microtubule; mitotic spindle; signal transduction; phosphorylation; cancer; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The microtubule cytoskeleton, which consists of dynamic polymers of alpha/beta tubulin heterodimers, organizes the cytoplasm and is essential for chromosome segregation during mitosis. My thesis addresses the significance and potential interplay between four distinct microtubule-regulatory proteins. LÄS MER

  5. 19. Genetic and functional analysis of the adaptive immune response

    Författare :Marco Mandolesi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The cells of the adaptive immune system rely on somatic recombination of V, D and J genes to obtain a vast range of specificities. T cells use four chains encoded by three genomic loci, to produce alpha/beta or gamma/delta T cell receptors (TCRs). LÄS MER

  7. 20. Immunomodulation of collagen-induced arthritis

    Författare :Lars Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :autoimmunity; arthritis; collagen type II; immunomodulation; vitamin D; parasite;

    Sammanfattning : Collagen-induced arthritis (CIA) is an experimental autoimmune disease sharing many features with human rheumatoid arthritis (RA). CIA development is dependent on T-cells but anti-collagen type II (anti-CII) antibody production by B-cells is also important. LÄS MER