Sökning: "mitotic spindle"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden mitotic spindle.

  1. 1. Microtubule and spindle pole body regulation in the budding yeast mitotic spindle

    Författare :Marjan Abbasi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The microtubule organizing center (MTOC) is a specialized structure with a main function in microtubule (MT) nucleation and organization. In higher eukaryotes, the main MTOC is known as the centrosome, and its functional equivalent in yeast is the spindle pole body (SPB). LÄS MER

  3. 2. The roles of inner nuclear membrane proteins during interphase and mitosis

    Författare :Veronica J. Larsson; Einar Hallberg; Neus Visa; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Samp1; mitotic spindle; centrosome; LINC complex; Lamina; Sun1; mitosis; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nuclear envelope (NE) consists of two concentric membranes, the outer nuclear membrane (ONM) and the inner nuclear membrane (INM). The LINC (linker of nucleoskeleton and cytoskeleton) complex spans both the ONM and the INM connecting the cytoskeleton to the nucleoskeleton and chromatin. LÄS MER

  4. 3. Characterization of the inner nuclear membrane protein Samp1, during interphase and mitosis

    Författare :Veronica J. Larsson; Einar Hallberg; Katharine S. Ullman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Samp1; LINC complex; nuclear lamina; MCLIP; nuclear envelope; spindle assembly; spindle stability; k-fiber; gamma tubulin; Aurora B; Haus6; Augmin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The nucleus, a hallmark in eukaryotic cells, contains the genome separating it from molecules in the cytoplasm. The nucleus is surrounded by a nuclear envelope consisting of two concentric membranes, the outer nuclear membrane and the inner nuclear membrane, the nuclear lamina and nuclear pore complexes. LÄS MER

  5. 4. Regulation of tubulin heterodimer partitioning during interphase and mitosis

    Författare :Per Holmfeldt; Martin Gullberg; Pontus Aspenström; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microtubule; mitotic spindle; signal transduction; phosphorylation; cancer; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The microtubule cytoskeleton, which consists of dynamic polymers of alpha/beta tubulin heterodimers, organizes the cytoplasm and is essential for chromosome segregation during mitosis. My thesis addresses the significance and potential interplay between four distinct microtubule-regulatory proteins. LÄS MER

  7. 5. The Drosophila POU/Oct factors: multifaceted proteins

    Författare :Priya Gohel; Ylva Engström; Mariana Wolfner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; POU Oct factors; transcriptional regulation; innate immunity; developmental processes; mitotic spindles; chromosome segregation; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Dysregulation of physiological and cellular processes underlies various pathological conditions, including cancer and inflammatory disorders. Unraveling the molecular mechanisms driving these processes is crucial. LÄS MER