Sökning: "voltage gated potassium channel"

Visar resultat 6 - 10 av 25 avhandlingar innehållade orden voltage gated potassium channel.

  1. 6. Voltage-Sensor Domains of Ion Channels : Physiology, Regulation, and Role in Disease

    Författare :Michelle Nilsson; Antonios Pantazis; Fredrik Elinder; Henry M. Colecraft; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Brain function depends on the ability of neurons to sense and respond to electricity, which is mediated by small modules in the neuronal membrane called voltage-sensor domains (VSDs). Disruption of VSD function can cause neurological disease such as epilepsy. LÄS MER

  3. 7. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods

    Författare :Sofia E. Unnerståle; Lena Mäler; Jason Schnell; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptide-lipid interaction; paddle domain; voltage gating; voltage sensor domain; micelle; phospholipid bicelle; solution structure; HAMP domain; nuclear magnetic resonance spectroscopy; circular dichroism spectroscopy; nonspecific interaction; Biophysics; biofysik;

    Sammanfattning : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. LÄS MER

  4. 8. Metabolic signals and the ATP-sensitive potassium channel in the pancreatic beta-cell

    Författare :Robert Bränström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ATP-regulated K channel; pancreatic [beta]-cell oscillations; [alpha]-ketoisocaproate; long chain acyl-CoA esters; Kir6.2 SUR1 structure-function.;

    Sammanfattning : ATP-sensitive K+ (KATP) channels are widely distributed in a variety of tissues and cell types. KATP channels are comprised of two subunits, a pore forming subunit (Kir6.x) and a regulatory sulfonylurea receptor (SURx). Both subunits are required for fully functional channels. LÄS MER

  5. 9. Calcium transport in the Pacific oyster, Crassostrea gigas - in a changing environment

    Författare :Kirsikka Sillanpää; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Climate changes; Ussing chambers; Calcium uptake; Sodium potassium ATPase; Calcium ATPase; Sodium calcium exchanger; Calcium channel; Hemocytes; Mantle epithelium;

    Sammanfattning : Pacific oyster, Crassostrea gigas, is globally one of the most important farmed bivalve species. A prominent features of the C. gigas is the thick CaCO3 shell covering the body of the animal and protecting it from the environment. LÄS MER

  7. 10. Site and Mechanism of Action of Resin Acids on Voltage-Gated Ion Channels

    Författare :Malin Silverå Ejneby; Fredrik Elinder; Johan Brask; Dirk Snyders; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Voltage-gated ion channels are pore-forming membrane proteins that open or close their gates when the voltage across the membrane is changed. They underlie the electrical activity that enables the heart to pump blood and the brain to receive and send signals. LÄS MER