Sökning: "voltage gated potassium channel"

Visar resultat 21 - 25 av 25 avhandlingar innehållade orden voltage gated potassium channel.

1. 21. Ion homeostasis in control of stem cell proliferation

   Författare :Shaimaa Abdelhady; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The ion homeostasis is critically maintained in all cells by a combined effort from various ion channels, transporters, pumps, and gap junctions. Ion fluxes are essential in excitable cells as they regulate the excitability of the cells and initiate and propagate action potentials. LÄS MER

3. 22. Biotransformation of the antineoplastic drug oxaliplatin : importance for effects and side effects

   Författare :Elin Jerremalm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Oxaliplatin is a platinum-based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin for palliative and adjuvant treatment of metastatic colorectal cancer. LÄS MER

4. 23. Detecting the dynamics of single biomolecules

   Författare :Stefan Wennmalm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : This thesis is concerned with the detection of single biomolecules. Through detection of individual molecules it can be clarified whether a behavior which has been observed in a population is representative for all molecules. For detection confocal fluorescence microscopy was used, in particular Fluorescence Correlation Spectroscopy (FCS). LÄS MER

5. 24. Biophysical studies of membrane associated peptides

   Författare :Jesper Lind; Astrid Gräslund; Lena Mäler; Christian Griesinger; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR; spectroscopy; membrane interaction; bicelles; Chemistry; Kemi; Biophysics; biofysik;

   Sammanfattning : A large part of the processes in living organisms involves proteins acting in a biological membrane. Biophysical studies on isolated model systems can give important understandings of the complicated biological mechanisms in the membrane. In this thesis peptide membrane interaction mechanisms are studied in several different systems. LÄS MER

7. 25. Identification and investigation of gamma-secretase associated proteins from brain

   Författare :Yasuhiro Teranishi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. The pathological hallmarks in the AD brain are extracellular deposition of amyloid plaques, mainly composed of the amyloid β-peptide (Aβ), and intracellular neurofibrillary tangles made of hyperphosphorylated tau. LÄS MER