Sökning: "virus diseases"

Visar resultat 36 - 40 av 291 avhandlingar innehållade orden virus diseases.

  1. 36. Molecular Diagnosis of Common Viral Infectious Diseases Based on Real-Time PCR

    Författare :Nahla Mohamed; Jonas Blomberg; Jan Fohlman; Elgh Fredrik; Uppsala universitet; []
    Nyckelord :Molecular biology; Microbiology; Virology; rTth DNA polymerase; UNG; QPCR; RNA virus; broadly targeted PCR; Molekylärbiologi;

    Sammanfattning : Molecular biology has become an integral part of the diagnosis of infectious diseases. Recently, quantitative real-time PCR (QPCR) methods (often in the form of so-called TaqMan® systems) have been developed for the diagnosis of a wide range of infectious diseases; these techniques found valuable clinical application in the diagnosis and evaluation of progress and therapeutic success of viral diseases. LÄS MER

  2. 37. Epidemiology and clinical importance of GB virus C/hepatitis G virus

    Författare :Robert Halasz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :GBV-C; HGV; prevalence; transmission; children; fulminant hepatic failure; clinical importance;

    Sammanfattning : GB virus C (GBV-C) or hepatitis G virus (HGV) is a recently discovered enveloped RNA virus belonging to the Flaviviridae family. GBV-C/HGV has been suggested to be a causative agent of non-A-non-E hepatitis. However, several contradictory observations cast doubts that it actually causes hepatitis. LÄS MER

  3. 38. Molecular characterization of the Tick-borne encephalitis virus : Environments and replication

    Författare :Wessam Melik; Magnus Johansson; Sonja Best; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The flavivirus genus is of major concern for world morbidity and mortality and includes viruses causing both encephalitic as well as hemorrhagic diseases. The incidence of Tick-borne encephalitis is increasing in many European countries and several reports have emphasized the expansion of the main vector, Ixodes ricinus. LÄS MER

  4. 39. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Författare :Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. LÄS MER

  5. 40. Structural and Functional Studies on Evolutionary Repurposing of H-box/NC-proteins : From Host Factor to Virus Protein

    Författare :Anna Wehlin; Eleonore von Castelmur; Per Hammarström; Maria Sunnerhagen; Lars-Göran Mårtensson; Lars-Anders Carlson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Picornaviridae are a large family of biomedically important viruses causing diseases such as the common cold, hepatitis A and polio in humans and foot-and-mouth disease in cattle. These diseases have great impact on people’s everyday life and cause economical losses all around the world. To date, no antiviral treatments are available. LÄS MER