Sökning: "Eleonore von Castelmur"

Hittade 3 avhandlingar innehållade orden Eleonore von Castelmur.

  1. 1. Small angle scattering as a tool to study protein structure and interactions

    Författare :Zuzanna Pietras; Maria Sunnerhagen; Eleonore von Castelmur; Cy Jeffries; Lars-Göran Mårtensson; Annette Langkilde; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This thesis uses small angle X-ray and neutron scattering (SAXS/SANS) to gain structural and functional insight into the molecular regulation of critical life processes in prokaryotic and eukaryotic species. The presented studies highlight the strength of combining low-resolution structure determination with biophysical and in silico modelling methods to extensively characterize proteins and their interactions. LÄS MER

  3. 2. Structural, Dynamic and Functional Studies of USP14 : A Proteasome-Associated Deubiquitinating Enzyme Regulating Protein Degradation

    Författare :Johannes Salomonsson; Maria Sunnerhagen; Alexandra Ahlner; Eleonore von Castelmur; Pau Bernadó; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Ubiquitin-Specific Protease 14 (USP14) is a proteasome-associated deubiquitinating enzyme (DUB) involved in regulation of protein degradation and recycling of ubiquitin. USP14 consists of a Ubl domain connected to a USP domain via a flexible linker. LÄS MER

  4. 3. Structural and Functional Studies on Evolutionary Repurposing of H-box/NC-proteins : From Host Factor to Virus Protein

    Författare :Anna Wehlin; Eleonore von Castelmur; Per Hammarström; Maria Sunnerhagen; Lars-Göran Mårtensson; Lars-Anders Carlson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Picornaviridae are a large family of biomedically important viruses causing diseases such as the common cold, hepatitis A and polio in humans and foot-and-mouth disease in cattle. These diseases have great impact on people’s everyday life and cause economical losses all around the world. To date, no antiviral treatments are available. LÄS MER