Sökning: "surgical specialization"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden surgical specialization.

  1. 1. Emergent colon cancer and postoperative complications - risks and management

    Författare :Örvar Arnarson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; postoperative complications; bridge to surgery; emergency surgery; surgical specialization; Cancer registry;

    Sammanfattning : Background:Colorectal cancer in the third most diagnosed cancer in Sweden and the second most common cause of cancer-related death in Sweden and worldwide. 10-30% of the cases present as emergencies, of which 80% are caused by large bowel obstruction (LBO). LÄS MER

  3. 2. Composite Regenerative Scaffolds

    Författare :Elle Edin; Jöns Hilborn; May Griffith; Alicia El Haj; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nerve; neurite; regeneration; PEDOT; PEDOT:Tosylate; electrostimulation; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Sammanfattning : Regenerative medicine and tissue engineering solutions of heavily innervated tissues are at this point lacklustre. This thesis expands our knowledge of appropriate acellular scaffolds for tissue repair in general and nerve regeneration in particular. LÄS MER

  4. 3. Glioblastoma heterogeneity and plasticity : Investigating the roles of BMP4 and SOX2

    Författare :Erika Dalmo; Bengt Westermark; Fredrik J. Swartling; Lene Uhrbom; Ana Martin-Villalba; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; SOX2; BMP4; senescence; plasticity; Oncology; Onkologi; Medicinsk vetenskap; Medical Science; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : The malignant primary brain tumor glioblastoma has a dismal prognosis and is distinguished by its heterogeneous character. Current treatment with surgical resection, radiotherapy and adjuvant chemotherapy with the alkylating agent temozolomide does not provide a cure, but simply prolongs survival by a few months. LÄS MER

  5. 4. Modeling glioblastoma growth patterns and their mechanistic origins

    Författare :Emil Rosén; Sven Nelander; Rebecka Jörnsten; Philip Gerlee; Kristin Swanson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; glioblastoma; invasion; image analysis; neural networks; Mathematics with specialization in Applied Mathematics; Matematik med inriktning mot tillämpad matematik; Oncology; Onkologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Glioblastoma (GBM) is the most common and aggressive primary brain cancer. GBM cells migrate away from the primary lesion and invade healthy brain tissue. The invading cells escape surgical resection, radiotherapy and develop resistance to chemotherapy. Consequently, despite treatment, recurrence is inevitable, and survival is only 14 months. LÄS MER

  7. 5. Modeling and investigations of high-grade glioma to understand tumorigenesis and heterogeneity

    Författare :Nagaprathyusha Maturi; Lene Uhrbom; Helena Carén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; diffuse pediatric-type high-grade glioma; cell of origin; heterogeneity; serum culture; glioblastoma stem cell; chromatin accessibility; cross-species conservation; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Glioblastoma (GBM) is the most common primary malignant brain tumor. As per 2021 WHO classification, the corresponding diagnosis in children is called diffuse pediatric-type high-grade glioma (pHGG). In both cases tumors are histone 3 (H3) and isocitrate dehydrogenase 1/2 (IDH1/2) wildtype (wt). LÄS MER