Sökning: "cross-species conservation"

Hittade 2 avhandlingar innehållade orden cross-species conservation.

1. 1. Modeling and investigations of high-grade glioma to understand tumorigenesis and heterogeneity

   Författare :Nagaprathyusha Maturi; Lene Uhrbom; Helena Carén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; diffuse pediatric-type high-grade glioma; cell of origin; heterogeneity; serum culture; glioblastoma stem cell; chromatin accessibility; cross-species conservation; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : Glioblastoma (GBM) is the most common primary malignant brain tumor. As per 2021 WHO classification, the corresponding diagnosis in children is called diffuse pediatric-type high-grade glioma (pHGG). In both cases tumors are histone 3 (H3) and isocitrate dehydrogenase 1/2 (IDH1/2) wildtype (wt). LÄS MER

3. 2. Influence on the transcriptome of Tec family kinases with special emphasis on Btk

   Författare :Hossain M Nawaz; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Over the last decade, scientists all over the world have profoundly used gene expression profiling based on microarray. Affymetrix is considered as the one of the pioneer platforms in the field of microarray technology. LÄS MER