Sökning: "ssx"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet ssx.

  1. 1. Implementation and development of serial synchrotron crystallography at MAX IV

    Författare :Bjelčić Monika; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ssx; time-resolved; crystallography; MAX IV LAboratory;

    Sammanfattning : Over the past decade, remarkable advancements in femtosecond X-ray free-electron lasers (XFELs) have brought about a profound transformation in structural biology. These XFELs have opened up exciting opportunities for conducting high-time resolution, room-temperature studies on protein structures and dynamics. LÄS MER

  3. 2. Time-resolved X-ray diffraction and solution scattering studies of Sensory Rhodopsin II in isolation and in complex with its transducer

    Författare :Giorgia Ortolani; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; light-activated membrane protein; microbial Rhodopsins; Sensory rhodopsin II; SRII; SRII:HtrII; transducer; SSX; XSS; time-resolved;

    Sammanfattning : Light is an important source of energy for many living organisms. Many life forms have therefore evolved cellular receptors that are able to sense light and thereby optimise conditions for photosynthesis and pho- totrophy. LÄS MER

  4. 3. Molecular mechanisms underlying the oncogenic function of SS18 and SSX

    Författare :Pádraig D'Arcy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The SS18 and SSX genes were initially identified based on their reoccurrence as fusion partners in synovial sarcoma. As a result of the specific chromosomal translocation t(X:18), the SS18 gene from chromosome 18 becomes fused with members of the SSX gene family on the X chromosome resulting in the generation of a novel chimeric fusion gene SS18-SSX. LÄS MER

  5. 4. Genetic Profiling in Soft Tissue Sarcoma

    Författare :Princy Francis; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; synovial sarcoma; prognosis; Cytology; SS18-SSX; intratumor heterogeneity; aCGH; array comparative genomic hybridization; gene expression analysis; microarray; cDNA; Soft tissue sarcoma; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Soft tissue sarcomas (STS) are a heterogeneous group of highly malignant mesenchymal tumors that account for ~1% of all malignancies. Frequent heterogeneity and pleomorphism along with suboptimal diagnostic reproducibility and insufficient prognostic markers make clinical management of these tumors difficult. LÄS MER

  7. 5. The biological role and clinical impact of SYT-SSX fusion gene and IGF-1R in synovial sarcoma

    Författare :Yuntao Xie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Synovial sarcoma; translocation; SYT-SSX; IGF-1R cyclin D1; cell cycle; proliferation; apoptosis.;

    Sammanfattning : Synovial sarcoma, which is a highly malignant soft tissue tumour occurring mainly in young and middle-aged adults, is characterized by the translocation t(X; 18)(p 11.2; q 11.2). LÄS MER