Sökning: "sodium currents"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden sodium currents.
1. Finding improved drug strategies for schizophrenia : Preclinical studies on lumateperone and sodium nitroprusside
Sammanfattning : Schizophrenia is a severe psychiatric disorder affecting approximately 20 million people worldwide. The disease consists of positive symptoms e.g. hallucinations, negative symptoms such as anhedonia, and cognitive deficits, e. LÄS MER
2. Tetrodotoxin-resistant sodium channels in neuropathic pain
Sammanfattning : Injury to the peripheral nervous system can cause neuropathic pain. Abnormal sodium channel activity has been implicated as a source of ectopic firing and changes in nociceptive threshold following nerve injury. LÄS MER
3. Mechanisms of adaptation in a mechanoreceptor : a study of mechanical and ionic factors in the crayfish stretch receptors
Sammanfattning : The stretch receptor organ of the crayfish, an analog to the human muscle spindle, is a unique preparation for the study of mechanotransduction. The organ consists of a rapidly and a slowly adapting receptor each composed of a receptor muscle fibre into which inserts the dendrites of a multipolar sensory neuron. LÄS MER
4. Mechanism of Action of the Antiarrhythmic Agent AZD7009
Sammanfattning : Atrial fibrillation (AF) is the most common tachyarrhythmia in the adult population and is a major cause of morbidity and mortality. AF can be terminated and sinus rhythm restored by prolonging the action potential duration (APD) and the refractory period. LÄS MER
5. Lightweight multifunctional composites : An investigation into ion-inserted carbon fibres for structural energy storage, shape-morphing, energy harvesting & strain-sensing
Sammanfattning : The transport sector accounts for around 26% of all greenhouse gas emissions in the European Union and United Kingdom. By reducing the mass of vehicles it is possible to reduce these emissions substantially.One way to reduce vehicle mass is to use multifunctional structures. LÄS MER