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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Internal Dosimetry Development and Evaluation of Methods and Models

    Författare :Lena M Jönsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; crypt cells; intestine; radionuclide; scintillation camera; sestamibi; activity quantification; conjugate view method; Monte Carlo simulation; internal dosimetry; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; medicinsk instrumentering; radiologi;

    Sammanfattning : Radionuclide therapy requires patient-specific planning of the absorbed dose to target volumes, in most cases tumours, in order to achieve an expected biological effect, taking into account that the absorbed doses to normal organs and tissues should be kept as low as reasonably achievable. Therefore, the calculation of absorbed doses has to be as accurate as possible. LÄS MER

  3. 2. Differentiation of renal oncocytoma from renal cell carcinoma by means of ⁹⁹Tc-Sestamibi SPECT/CT

    Författare :Antonios Tzortzakakis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Purpose: An increasing body of literature indicates the beneficial role of [99m]Tc-Sestamibi SPECT/CT in the non-invasive differentiation of renal oncocytoma (RO) from renal cell carcinoma (RCC). This thesis presents a comprehensive approach of [99m]Tc-Sestamibi SPECT/CT examination following the implementation of quantitative tools in addition to visual assessment. LÄS MER

  4. 3. Preoperative localisation of parathyroid adenoma in primary hyperparathyroidism using 99mTc-sestamibi SPECT/CT : an evolving scanning protocol

    Författare :Patricia Sandqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary hyperparathyroidism (pHPT) is caused by one or more hyperfunctional parathyroid gland causing an inappropriately high release of parathyroid hormone (PTH) in relation to the calcium concentration in the blood. PTH acts on the bones to release more calcium and on the kidneys to reabsorb calcium, causing hypercalcemia. LÄS MER

  5. 4. Cardiac side-effects of adjuvant radiotherapy for early breast cancer

    Författare :Gábor Gyenes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Early breast cancer; Radiation therapy; Ischemic heart disease; Side-effects; Microvascular domage; Long-term effects; Myocardial disease; Technetium 99-m sestamibi perfusion scintigraphy; Prospective study;

    Sammanfattning : It is well established that adjuvant radiotherapy (RT) reduces loco-regional recurrences in breast cancer. The effect on overall survival on the other hand is much debated. LÄS MER

  7. 5. Nuclear medicine imaging of breast cancer and regional lymph nodes

    Författare :Rimma Danielsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :breast neoplasm; scintimammography; diagnostic accuracy; triple diagnosis; axillary lymph node metastases;

    Sammanfattning : The aim of this thesis was to explore the role of nuclear medicine in diagnosis of primary breast carcinoma and regional lymph node involvement. The introduction includes a review over nuclear medicine techniques currently under investigation. LÄS MER