Sökning: "retinol"

Visar resultat 11 - 15 av 59 avhandlingar innehållade ordet retinol.

1. 11. Regulation of morphogen signalling during neural patterning in the Xenopus embryo

   Författare :Hooi Min Tan Grahn; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suppressor-of-fused; Gli; β-Catenin; Neural; Xenopus; FGF; Signalling; HtrA1; RDH10; Retinol dehydrogenase; Retinoic acid; Spemann s organizer; Induction; Gradient;

   Sammanfattning : Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xenopus embryo. LÄS MER

3. 12. Anaemia and iron deficiency in children and women in Tanzania. Effects of dietary iron intake, low iron bioavailability and supplementation with multiple micronutrient beverage

   Författare :Simon Tatala; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; serum ferritin; haemoglobin; multiple micronutrient beverage; dietary iron intake; anaemia; serum retinol; iron deficiency; children and Tanzania; pregnant women; iron bioavailability;

   Sammanfattning : Anaemia was investigated in a rural Tanzanian community to determine its magnitude and causative factors in different population groups. Nutritional anaemia resulting mainly from a diet with a low bioavailability of iron affected more than half of the total number of women and children. LÄS MER

4. 13. The molecular biology of retinoid metabolism : identification of an 11-cis retinol dehydrogenase in the retinal pigment epithelium

   Författare :András Simon; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :11-cis retinol; 11-cis retinol dehydrogenase; chromophore; 11-cis retinaldehyde; 9-cis retinol; 9-cis retinol dehydrogenase; retinal pigment epithelium; vitamin A; short-chain alcohol dehydrogenase;

   Sammanfattning : Vitamin A derivatives (retinoids) are essential molecules in the course of embryonic development, postnatal growth and adult physiology. The physiological functions of retinoids are thought to be mediated mainly by retinoic acid which regulates the expression of various genes, and 11-cis retinaldehyde, which is the common chromophore of visual pigments. LÄS MER

5. 14. Studies of the vitamin A transporting protein complex retinol-binding protein-transthyretin

   Författare :Håkan Melhus; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

7. 15. Megalin, an Endocytotic Receptor with Signalling Potential

   Författare :Mårten Larsson; Lars Rask; Bo Åkerström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Megalin; LRP-2; Postsynaptic density-95; Retinol-binding protein; Oligodendrocytes; Central nervous system; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : Megalin is an endocytotic receptor belonging to the low-density lipoprotein family. It has often been viewed only as merely a scavenger receptor of absorptive and secretory epithelia. Recent work has revealed that the megalin intracellular domain contains several motifs potentially binding proteins involved in signal transduction. LÄS MER