Sökning: "LRP-2"

Hittade 3 avhandlingar innehållade ordet LRP-2.

  1. 1. The megalin receptor

    Författare :Göran Hjälm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; calcium; parathyroid; gp330; megalin; LRP-2; LDL-receptor super family; endogenous retroviruse; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Ionized calcium is a major player in the living organism. Its importance in both intra- and extracellular mechanisms have been studied in a broad number of publications. LÄS MER

  2. 2. Megalin, an Endocytotic Receptor with Signalling Potential

    Författare :Mårten Larsson; Lars Rask; Bo Åkerström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Megalin; LRP-2; Postsynaptic density-95; Retinol-binding protein; Oligodendrocytes; Central nervous system; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Megalin is an endocytotic receptor belonging to the low-density lipoprotein family. It has often been viewed only as merely a scavenger receptor of absorptive and secretory epithelia. Recent work has revealed that the megalin intracellular domain contains several motifs potentially binding proteins involved in signal transduction. LÄS MER

  3. 3. Transcriptional regulation of genes expressed in the parathyroid gland

    Författare :Anders Knutson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : A dynamic interplay between promoter sequences and transcription factors ensures that genes are expressed at appropriate levels in each cell throughout the body. In the present investigation, the promoters of two different genes encoding proteins involved in parathyroid cell function and calcium homeostasis were studied. LÄS MER