Sökning: "Eric Snoeck"

Hittade 1 avhandling innehållade orden Eric Snoeck.

1. 1. Safety and Efficacy Modelling in Anti-Diabetic Drug Development

   Författare :Bengt Hamrén; Mats O Karlsson; Eric Snoeck; Uppsala universitet; []
   Nyckelord :Pharmaceutical biosciences; pharmacokinetic; pharmacodynamic; mechanism-based; modelling; type 2 diabetes mellitus; tesaglitazar; PPAR; drug development; NONMEM; Farmaceutisk biovetenskap;

   Sammanfattning : A central aim in drug development is to ensure that the new drug is efficacious and safe in the intended patient population. Mathematical models describing the pharmacokinetic-pharmacodynamic (PK-PD) properties of a drug are valuable to increase the knowledge about drug effects and disease and can be used to inform decisions. LÄS MER