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Visar resultat 1 - 5 av 9 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Synthesis of Molecular Probes for Exploring the Human Consciousness, 5-HT7 Ligands and Salvinorins

    Författare :Pär Holmberg; Anders Karlén; Adolf Gogoll; Anette Johansson; Christer Sahlberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; serotonin system; opioid system; selective 5-HT7 agonist; 3-aminchromans; salvinorin A; selective kappa opioid receptor; mental disorders; consciousness; regioselective oxidation; enzymatic kinetic resolution; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : In this study, we have addressed the serotonergic and the opioid system within the CNS. Both systems are of outmost importance in the etiology of disease states, especially mental disorders. LÄS MER

  2. 2. Organocatalytic Transformations with N-Heterocyclic Carbenes - An Investigation of Ionic Liquids as NHC Precatalysts and Aerobic Oxidative Esterifications

    Författare :Linda Ta; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; N-heterocyclic carbene; ionic liquid; multi-component reaction; aerobic oxidation; OTHO; Organocatalysis; green chemistry;

    Sammanfattning : The call for more sustainable processes in the chemical society has led to the development of the field of green chemistry. The Twelve Principles of Green Chemistry serve as guidelines for the design of processes. LÄS MER

  3. 3. N-Heterocyclic Carbene Catalysis in Organic Synthesis - A Green Chemistry Approach

    Författare :Linda Ta; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; aerobic oxidation; ionic liquid; sustainability; NHC catalysis; oxidative NHC catalysis; green chemistry; OTHO; Organocatalysis;

    Sammanfattning : The twelve principles of green chemistry were created as a response to the multiple environmental issues caused by the release of waste from the chemical industry. The principles acts as a guide in the development of sustainable chemical processes for the syntheses of important molecules needed to sustain our living standards. LÄS MER

  4. 4. C-H Activation Reactions Mediated by Pd Based Heterogeneous Catalysts : Regioselective Formation of C-O and C-X Bonds

    Författare :Maitham Majeed; Centrum för analys och syntes; []
    Nyckelord :C-H Activation; N-heterocyclic carbenes; palladium; polymer supported Pd II ; undirected acetoxylation; directed halogenation; continuous flow; reduced graphene oxide supported Pd II ;

    Sammanfattning : New classes of N-heterocyclic carbene-palladium(II) complexes containing either a vinyl group in different positions or an anthracene tag in the backbone of the N-heterocycle were synthesized and fully characterized. The vinyl based complexes were copolymerized with divinylbenzene to fabricate robust polymer-supported NHC-Pd(II) systems, while the anthracene based complexes were π-stacked onto the surface of reduced graphene oxide (rGO) producing immobilized catalysts with interesting features. LÄS MER

  5. 5. Synthesis of oligosaccharides for structural, conformational and molecular recognition investigations

    Författare :Peter Söderman; Inge Lundt; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : Carbohydrates are involved cell-cell interaction. Synthesis of small and medium sized oligosaccharides is important to gain more understanding about the their physical properties that are crucial for their action in molecular recognition events. LÄS MER