Sökning: "reactive oxygen species ROS"

Visar resultat 16 - 20 av 212 avhandlingar innehållade orden reactive oxygen species ROS.

1. 16. Characteristics of Particulate Emissions from Low Temperature Combustion and Renewable Fuels : Aerosol Mass Spectrometry of Refractory Carbonaceous Particles

   Författare :Vilhelm Malmborg; NanoLund: Centre for Nanoscience; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Emissions; Soot; BC; BrC; ROS; SP-AMS; MiniCAST; Diesel Engine; HVO; RME; Cook Stove; Emissions; Soot; BC; BrC; SP-AMS; ROS; MiniCAST; Diesel Engine; HVO; RME; Cook Stove;

   Sammanfattning : Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. LÄS MER

3. 17. Intracellular radicals in neutrophils - processing and functional implications

   Författare :Halla Björnsdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophil; reactive oxygen species; neutrophil extracellular traps;

   Sammanfattning : Neutrophils are the most abundant leukocyte in human blood and essential components of our defense against microbial pathogens. These cells can neutralize microbial pathogens by phagocytosis, which involves engulfment and degradation of microbes intracellularly, as well as by the formation of neutrophil extracellular traps (NETs), which are structures released from neutrophils made up of DNA and proteins that capture microbes extracellularly. LÄS MER

4. 18. Mechanisms of leukemia-induced immunosuppression

   Författare :Johan Aurelius; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia; Immunosuppression; Immunotherapy; Reactive oxygen species; PARP-1; NK cells; T cells;

   Sammanfattning : This thesis aimed to define the role of reactive oxygen species (ROS), produced by the NADPH oxidase of myeloid cells, in the regulation of lymphocyte function with focus on ROS-induced dysfunction of natural killer (NK) cells and T lymphocytes in myeloid leukemia. In Paper I, a novel mechanism is presented by which specifically activated T lymphocytes evade inactivation by ROS after antigen presentation. LÄS MER

5. 19. Energy metabolism and angiogenesis in atherosclerosis and cancer

   Författare :Matias Ekstrand; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Hypoxia; Reactive oxygen species; Intussusceptive angiogenesis;

   Sammanfattning : Energy metabolism requires supply of glucose and oxygen. In atherosclerotic plaques and cancer tumors, there are local areas with mismatch in demand and supply of oxygen and nutrients. The resulting cellular energy imbalance may promote energy failure and stimulation of angiogenesis. LÄS MER

7. 20. Targeting NOX2 in cancer

   Författare :Ebru Aydin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; reactive oxygen species; immunotherapy; nox2; nk cells; melanoma; histamine; metastasis; leukemia; aml; cml; kras; mpd;

   Sammanfattning : Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a critical role in defense against bacteria and other microorganisms. LÄS MER