Sökning: "puumala virus"

Visar resultat 6 - 10 av 20 avhandlingar innehållade orden puumala virus.

  1. 6. Human antibody responses to hantavirus recombinant proteins & development of diagnostic methods

    Författare :Fredrik Elgh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Puumala virus; hantavirus infections; recombinant proteins; capsid; humoral immunity; immunoassay;

    Sammanfattning : Rodent-borne hantaviruses (family Bunyaviridae) cause two distinct human infections; hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS is a common viral zoonosis, characterized by fever, renal dysfunction and hemostatic imbalance. LÄS MER

  3. 7. Puumala hantavirus : immune responses and vaccines

    Författare :Cristina de Carvalho Nicacio; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hantavirus; Puumala virus; nucleocapsid protein; neutralizing antibodies; Fab fragment; combinatorial library; phage-display; IgA; cellular immunity; cross-protection; intranasal vaccination;

    Sammanfattning : Hantaviruses (family Bunyaviridae) is a group of closely related zoonotic rodent-borne viruses that are transmitted to humans through inhalation of infected rodent excreta. They cause hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS) with varying degree of severity depending on the causative virus. LÄS MER

  4. 8. Genetic and antigenic characterisation of Puumala virus in voles and man

    Författare :Jan Hörling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The present study has focused on the genetic and antigenic characteristics of Puumala (PUU) virus, the causative agent of nephropathia epidemica (NE). An assay for detection of neutralising antibodies to PUU virus was developed. LÄS MER

  5. 9. Cardiopulmonary involvement in Puumala hantavirus infection

    Författare :Johan Rasmuson; Clas Ahlm; Anders Blomberg; Jamshid Pourazar; Gregory J. Mertz; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemorrhagic fever with renal syndrome; hantavirus; echocardiography; respiratory function tests; computed tomography; bronchoalveolar lavage; biopsy; cytotoxic T cells; disease severity; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Puumala hantavirus (PUUV) causes hemorrhagic fever with renal syndrome in Europe. After inhalation of virus shed by bank voles, the virus systemically targets the vascular endothelium leading to vascular dysfunction and leakage. LÄS MER

  7. 10. Genomic Organization and Capsid Architecture of Ljungan Virus : a Novel Member of the Picornaviridae

    Författare :Susanne Johansson; Michael Lindberg; Einar Everitt; Tapani Hovi; Högskolan i Kalmar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Virologi; Virologi; Virology;

    Sammanfattning : Ljungan virus är ett virus som isolerades i Sverige i mitten på nittiotalet. Under perioden 1989-1992 avled flera svenska elitorienterare plötsligt i hjärtmuskelinflammation. Man misstänkte att orienterarna kunde ha utsatts för en vektorburen infektion eftersom de exponeras för djur som finns i skog och mark under träning och tävling. LÄS MER