Sökning: "phage-display"
Visar resultat 1 - 5 av 92 avhandlingar innehållade ordet phage-display.
1. Selection and design in antibody phage display
Sammanfattning : The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. LÄS MER
2. Discovery of targets for tumor immunotherapy using phage display technology
Sammanfattning : This thesis has focused on the development of methods and their applications for the identification of antibodies reactive with tumor associated antigens (TAA). The phage display technology provides a powerful mean to generate antibodies potentially useful for tumor immunotherapy. LÄS MER
3. Using peptide-phage display to capture conditional motif-based interactions
Sammanfattning : This thesis explores the world of conditional protein-protein interactions using combinatorial peptide-phage display and proteomic peptide-phage display (ProP-PD). Large parts of proteins in the human proteome do not fold in to well-defined structures instead they are intrinsically disordered. LÄS MER
4. Biomolecular recognition : recombinant antibodies, phage display and eukaryotic cloning systems
Sammanfattning : .... LÄS MER
5. Combinatorial Methodology. Screening for affinity specific ligands to biological and artificial receptors
Sammanfattning : Combinatorial screening methodology has been employed to select new affinity specific ligands to bilogical and artificial receptors. The screening methodology, in particular screening of combinatorial phage display peptide libraries against target molecules differing in function and shape, is focused upon. LÄS MER