Sökning: "platelet"

Visar resultat 21 - 25 av 485 avhandlingar innehållade ordet platelet.

  1. 21. Platelet activation and cytokine release during experimental extracorporeal circulation

    Författare :Katrin Adrian; Göteborgs universitet; []
    Nyckelord :ECMO; blood-biomaterial interaction; platelets; platelet activation; cytokines; systemic inflammatory response;

    Sammanfattning : .... LÄS MER

  3. 22. Platelet transfusions in hematological disorders

    Författare :Cecilia Karlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelets are important for clot formation and vascular integrity. Thrombocytopenic patients with hematological disorders are at risk of bleeding and platelet transfusions are important in supportive care and treatment of lite-threatening bleedings. LÄS MER

  4. 23. Immobilization as a risk factor for arterial and venous thrombosis

    Författare :Karin Arinell; Ole Frøbert; Kjeld Christensen; Tal Hörer; Joakim Alfredsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; arterial thrombosis; atherosclerosis; cystatin C; cholesterol; platelet activation; platelet aggregation; immobilization;

    Sammanfattning : Aim: Immobilization and a sedentary lifestyle are correlated with an elevated risk of both arterial and venous thrombosis. The goal of this research was to investigate whether markers associated with cardiovascular disease risk are altered during long term immobilization in a human model and in the brown bear, which survives annual cycles of long-term immobilization. LÄS MER

  5. 24. Platelets – Multifaceted players in tumor progression and vascular function

    Författare :Yanyu Zhang; Anna-Karin Olsson; Gertraud Orend; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER

  7. 25. Genetic studies on cardiovascular disease - identification of novel drug targets

    Författare :Stefan Amisten; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Medicin människa och djur ; Medicine human and vertebrates ; platelet; single nucleotide polymorphism; myocardial infarction; stent; G-protein coupled receptor; P2Y; cytogenetics; Genetik; cytogenetik; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : The aim of this thesis was to identify novel potential drug targets of cardiovascular disease with a focus on G-protein coupled receptors. We identified a common genetic variant of the ATP receptor P2Y11, where an alanine is substituted with a threonine at position 87 of the P2Y11 receptor that increases the risk of developing acute myocardial infarction. LÄS MER