Sökning: "phase I clinical trial"
Visar resultat 1 - 5 av 98 avhandlingar innehållade orden phase I clinical trial.
1. Mantle cell lymphoma strategies in primary treatment
Sammanfattning : Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. LÄS MER
2. Improved oncological treatment of anal cancer
Sammanfattning : Background: Squamous cell cancer of the anus (SCCA) is a rare malignancy, but the incidence is increasing. It isassociated with humman papilloma virus infection. The standard treatment is radiotherapy (RT) combined withchemotherapy, usually 5-fluorouracil (5FU)/Mitomycin C (MMC). LÄS MER
3. Exploring Cancer Drugs In Vitro and In Vivo : With Special Reference to Chemosensitivity Testing and Early Clinical Development
Sammanfattning : The aims of this thesis were to investigate the utility of in vitro drug sensitivity testing to optimize the use of cancer chemotherapy and to assess the properties of a new cancer drug in a phase I clinical trial. Tumour cells from patients were analysed with the short-term Fluorometric Microculture Cytotoxicity Assay (FMCA). LÄS MER
4. Patients in Clinical Cancer Trials : Understanding, Motivation and Hope
Sammanfattning : The overall aim of this thesis was to study participants' understanding of clinical cancer trials, and their motivation for participation. Of particular interest was the question of whether the patients hoped for a cure resulting from the trial. LÄS MER
5. Porcelain veneering of titanium : clinical and technical aspects
Sammanfattning : Guld- och andra legeringar har i många år använts som material vid framställning av kronor och broar för ersättning av skadade eller förlorade tänder. Emellertid har tvivel uppstått kring lämpligheten av att använda guldlegeringar i tandersättningar, då guld har visat sig kunna ge biverkningar i form av allergiska reaktioner. LÄS MER