Sökning: "phase 1 trials"
Visar resultat 1 - 5 av 59 avhandlingar innehållade orden phase 1 trials.
Sammanfattning : The overall aim of this thesis was to study participants' understanding of clinical cancer trials,and their motivation for participation. Of particular interest was the question of whether thepatients hoped for a cure resulting from the trial. LÄS MER
Sammanfattning : This thesis consists of four articles whose theme in common is the class of phase type distributions. In the first article an EM algorithm is presented to estimate the parameters of a phase type distribution of fixed order. Also, it is shown that the algorithm can be used to approximate other continuous distributions by phase type distributions. LÄS MER
Sammanfattning : The first step in HIV - 1 entry is the interaction between viral envelope glycoprotein gp120 and CD4 receptor on permissive host cells. The interaction initiates a series of sequential conformational rearrangements that exposes epitopes involved in interaction with co - receptors. LÄS MER
Sammanfattning : Clinical trials are an established methodology for evaluation of the effects of a new medical treatment. These trials are usually divided into several phases, namely phase I through IV. The earlier phases (I and II) are relatively small and have a more exploratory nature. LÄS MER
5. On the Extraction of Essential Oils by Supercritical Carbon Dioxide and its Influence on the Mesomorphic Phase Structures
Sammanfattning : A comparison of essential oils from leaves of Eucalyptus camaldulensis Dehn. obtained by hydrodistillation (HD) and supercritical carbon dioxide (SC-CO2) extraction is presented. Selected major components of the oils showed a predominance of higher molecular weight components in the SC-CO2 extracts than in those obtained by HD. LÄS MER