Sökning: "phase I II trial"

Visar resultat 1 - 5 av 102 avhandlingar innehållade orden phase I II trial.

  1. 1. Mantle cell lymphoma strategies in primary treatment

    Författare :Alexandra Albertsson Lindblad; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mantle cell lymphoma; registry data; Clinical Trial; Phase I; Clinical Trial; Phase II; rituximab; bendamustine; lenalidomid; ibrutinib; ADCC; in vitro model; TP53 mutations; watchful waiting; mantle cell lymphoma; real-world data; lenalidomide; rituximab; bendamustin; ibrutinib; ADCC; TP53 mutation; CDKN2A; NGS; MIPI; Watchful waiting;

    Sammanfattning : Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. LÄS MER

  3. 2. Improved oncological treatment of anal cancer

    Författare :Otilia Leon; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anal cancer; chemotherapy; Radiotherapy; Prognosis and survival; phase I II trial; Cetuximab; metastatic;

    Sammanfattning : Background: Squamous cell cancer of the anus (SCCA) is a rare malignancy, but the incidence is increasing. It isassociated with humman papilloma virus infection. The standard treatment is radiotherapy (RT) combined withchemotherapy, usually 5-fluorouracil (5FU)/Mitomycin C (MMC). LÄS MER

  4. 3. Delayed Sleep Phase Disorder : Prevalence, Diagnostic aspects, Associated factors and Treatment concepts

    Författare :Katarina Danielsson; Agneta Markström; Broman Jan-Erik; Markus Jansson-Fröjmark; Lars von Knorring; Pallesen Ståle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; delayed sleep phase disorder; prevalence; diagnostic aspects; associated factors; light therapy and cognitive behavior therapy;

    Sammanfattning : Delayed sleep phase disorder (DSPD) is the most common circadian rhythm sleep disorder. Persons with DSPD have great difficulties falling asleep and waking up at conventional times. To diagnose DSPD this delayed sleep-wake rhythm should cause social impairment and distress for the individual. LÄS MER

  5. 4. Early Treatment of Class II Malocclusion With Excessive Overjet : evaluating oral health-related quality of life, randomised controlled trials on headgear activator treatment and costs

    Författare :Jenny Kallunki; Liselotte Paulsson; Lars Bondemark; Frank Weiland; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Orthodontics; Malocclusion; Class II; Oral health-related quality of life; cost analysis; Hälsa och samhälle; Health and society;

    Sammanfattning : Class II malocclusion with excessive overjet is one of the most common malocclusions among children and adolescents. In addition to increasing the risk for dental trauma, the malocclusion can also be related to bullying due to the prominent maxillary incisors. LÄS MER

  7. 5. Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

    Författare :Anna Sundlöv; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; PRRT; somatostatin analogs; pituitary function; renal function; dosimetry; 68Ga-DOTATATE; individualized treatment; neuroendocrine tumors;

    Sammanfattning : Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. LÄS MER