Sökning: "peritoneal dialysis PD"

Visar resultat 6 - 10 av 20 avhandlingar innehållade orden peritoneal dialysis PD.

1. 6. Impact of peritoneal solute transport rate on nutritional status and clinical outcome in peritoneal dialysis patients

   Författare :Sung Hee Chung; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adequacy of dialysis; comorbid diseases; fluid removal; inflammation; mortality; malnutrition; peritoneal dialysis; peritoneal solute transport rate; residual renal function.;

   Sammanfattning : The transport characteristics of the peritoneal membrane may be influenced by inflammation and various comorbid diseases (CMD) in peritoneal dialysis (PD) patients. On the other hand, the peritoneal solute transport rate (PSTR) may influence patient characteristics such as nutritional status as well as the clinical outcome of PD patients. LÄS MER

3. 7. Icodextrin metabolism in peritoneal dialysis : clinical and experimental studies

   Författare :Elvia Garcia Lopez; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Icodextrin is a glucose polymer which is used as osmotic agent to provide sustained ultrafiltration (UF) during the long (8-16 hours) dwell in end-stage renal disease patients undergoing peritoneal dialysis (PD). The aims of this thesis were to study: the metabolism of icodextrin in the peritoneal cavity and in the circulation of PD patients and non-uremic rats, the role of alpha-amylase in its hydrolysis, and the rate of breakdown of a synthetic maltoheptaose (G7) ex vivo which we propose as a novel measure of amylase mediated oligosaccharide metabolism. LÄS MER

4. 8. Hypoxia-inducible factors (HIFs) and biological responses, in hypoxia, inflammation and embryonic vascular development

   Författare :Maria Hägg; Göteborgs universitet; []
   Nyckelord :Embryonic stem cell; embryoid body; HIF-1a; hypoxia; VEGF; angiogenesis; vasculogenesis; peritoneal dialysis;

   Sammanfattning : ABSTRACT Low oxygen tension (hypoxia) is a major inducer of neovascularisation and evidence emerging has indicated that oxygen tension and hypoxia-inducible factors (HIFs), a family of oxygen-regulated heterodimeric transcription factors, may play important roles in vascular and hematopoietic development. This thesis has focused on studying molecular and cellular mechanisms, by which cells and organisms sense changes in oxygen tension, and how this signal is transduced by HIFs into downstream signalling. LÄS MER

5. 9. Mechanisms of transendothelial and tissue transport in the peritoneum. Experimental studies on rat

   Författare :Bert-Inge Rosengren; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nefrologi; Urologi; hyaluronan; interstitium; blood flow; rat; pore; inhibition; temperature; peritoneal dialysis; permeability; capillary; protein; passive; active; transport; transcytosis; vesicle; Urology; nephrology; small solute;

   Sammanfattning : In the present thesis, the quantitative role of active transport (transcytosis) in bulk transvascular protein movement in vivo was evaluated. Using chemical transcytosis inhibition (N-ethylmaleimide (NEM) and filipin), we were able to show that NEM actually increases endothelial permeability to macromolecules, probably as a result of unspecific toxic action on endothelial cells. LÄS MER

7. 10. Acute inflammation in peritoneal dialysis. Experimental studies in rats. Characterization of regulatory mechanisms

   Författare :Farhan Bazargani; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The predominant problems associated with peritoneal dialysis (PD) are ultrafiltration failure and peritonitis. PD maintains a state of intraperitoneal inflammation that affects the structure and function of the peritoneal membrane, potentially impairing ultrafiltration efficiency. LÄS MER