Sökning: "pancreas cancer"

Visar resultat 11 - 15 av 58 avhandlingar innehållade orden pancreas cancer.

  1. 11. Peptide Receptor Radionuclide Therapy in Neuroendocrine Neoplasms : Aspects of tumour characteristics, receptor recycling and peptide mass

    Författare :Ulrika Jahn; Anders Sundin; Mark Lubberink; Ulrike Garske-Román; Mona-Elisabeth Rootwelt-Revheim; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Peptide receptor radionuclide therapy PRRT ; Peptide; Small-Intestinal; Pancreatic; Dosimetry; Somatostatin receptor;

    Sammanfattning : Neuroendocrine neoplasm (NEN) can arise in any part of the body, but most commonly in the lungs, bronchi, and the gastrointestinal tract including the pancreas. They combine neuroendocrine and tissue-of-origin-specific characteristics; explaining different symptoms depending on the organ of origin. LÄS MER

  2. 12. Intraperitoneal 5-Fluorouracil treatment of cancer - clinical and experimental studies

    Författare :Mikael Öman; Peter Naredi; Larsolof Hafström; Johan Permert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; intraperitoneal; 5-fluorouracil; pancreas cancer; vasopressin; Xenon-clearance; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Background:Pancreas cancer is a most aggressive malignancy. More than 80% of patients diagnosed with pancreas cancer, exhibit such advanced disease, that curative surgery is impossible. Systemic chemotherapy prolongs survival to 5-9 months. LÄS MER

  3. 13. Role of PAK4 in pancreas development and breast cancer

    Författare :Miao Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : PAK4 is a Rho GTPase-regulated serine/threonine kinase that possesses critical functions in embryonic, neuronal and vascular development, immune defense and cancer. Constitutive PAK4 depletion causes embryonic lethality and mice with conditional PAK4 gene depletion in the heart and in the central nervous system displayed serious organ defects. LÄS MER

  4. 14. Insulin resistance in pancreatic cancer

    Författare :Bengt Isaksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pancreatic cancer; glucose transport; glucose metabolism; insulin signaling; insulin resistance; uncoupling proteins; obstructive jaundice; IAPP; risk factors.;

    Sammanfattning : The dismal prognosis of pancreatic cancer (PC) is related to metabolic complications of the tumor. Impaired glucose tolerance or diabetes due to insulin resistance, and cachexia are observed early and frequently in these patients. The basic mechanisms of PC-associated insulin resistance and weight loss are not fully understood. LÄS MER

  5. 15. Regulation of digestive organ. An experimental study on the role of CCK, Bile and EGF

    Författare :Bodil Ohlsson; Internmedicin - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; trophic effects; total parenteral nutrition; salivary glands; pancreaticobiliary diversion; pancreas; liver; intestinal mucosa; epidermal growth factor; cholecystokinin; biliodigestive shunt; Bile; bilary tract; serology; transplantation; Immunologi; serologi; Gastro-enterology; Gastroenterologi;

    Sammanfattning : Cholecystokinin (CCK) is known to exert secretory and trophic effects on the pancreas. Its release from the intestinal mucosa is regulated by pancresic proteases in the small intestine. However, knowledge about the type of responding exocrine cells and the time course of events during stimulation with CCK is lacking. LÄS MER