Sökning: "pain mechanism"

Visar resultat 36 - 40 av 97 avhandlingar innehållade orden pain mechanism.

  1. 36. Modulation of pain by immune factors : a study on interferon-g and its receptor in nociceptive transmission

    Författare :Kristina S Vikman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytokines; interferon-gamma; dorsal horn; hypersensitivity; nociceptive transmission; pain; GluR1; AMPA receptor; disinhibition; spontaneous activity; primary cell culture; two-compartment model; spinal cord.;

    Sammanfattning : Immune cytokines have been implicated as important neuromodulators, contributing to neuronal plasticity both in the adult and developing nervous system. In addition, they have been assigned a potential role in the generation of pathological pain, which may occur as a severe symptom following disease states in the nervous system. LÄS MER

  3. 37. Neuropeptide release in the rat dorsal horn in models of persistent pain : effects of opioids

    Författare :Abdullahi Warsame Afrah; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Axotomy; Inflammation; Long term potentiation; Capsaicin; Opioids; Cholecystokinin; Substance P; Glutamate; NMDA; Spinal cord; Microdialysis; Radioimmunoassay.;

    Sammanfattning : Nerve injury and tissue inflammation may lead to exaggerated responses to both noxious stimuli (hyperalgesia) and innocuous stimuli (allodynia). Altered release pattems of neurotransmitters in the dorsal hom of the spinal cord have been suggested to contribute to hyperalgesia and allodynia. LÄS MER

  4. 38. Hypothalamic and cortical control of jaw reflexes

    Författare :Kurt Å. Olsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cat; Oral projections; Cerebral cortex; Cytoarchitecture; Hypothalamus; Defence-Attack area; Jaw reflexes; Bruxism; Myofascial pain dysfunction;

    Sammanfattning : The subject of the thesis is a study of the projections from low threshold oral and face afferents to the cerebral cortex and of descending motor control mechanisms originating in the cerebral cortex or the hypothalamus and influencing the jaw reflexes.Cats anaesthetized with chi oral ose were used for the experiments. LÄS MER

  5. 39. Implications of autonomic nervous system and central inflammatory parameters for the perception of pain in fibromyalgia patients

    Författare :Diana Kadetoff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :fibromyalgia;

    Sammanfattning : Dysfunctions of the autonomic nervous system and of endogenous pain modulation have been reported in fibromyalgia (FM) patients. The dysregulation of the autonomic nervous system, i.e. LÄS MER

  7. 40. Nerve conduction and vibrotactile perception thresholds in female computer workers and hand-arm vibration-exposed male manual workers

    Författare :Helena Sandén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Computer use; Hand-arm vibration; Chronic upper limb pain; Nerve conduction; Vibrotactile perception threshold; Mood; Bicycle ergometer test; Temperature;

    Sammanfattning : Upper limb pain and disability are common problems, especially among working populations. The overall aim of this thesis was to investigate peripheral nerve function in the upper limb by nerve conduction test and vibration threshold test in working populations including female computer users (n = 82), hand-arm vibration-exposed male manual workers (n = 116), and female workers with chronic diffuse upper limb pain (n = 35). LÄS MER