Sökning: "Long term potentiation"

Visar resultat 1 - 5 av 31 avhandlingar innehållade orden Long term potentiation.

  1. 1. Developmental plasticity of the glutamate synapse: Roles of low frequency stimulation, hebbian induction and the NMDA receptor

    Författare :Joakim Strandberg; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPA receptor; Development; Glutamate; Hippocampus; Long-term depression; Long-term potentiation; NMDA receptor; Synaptic depression;

    Sammanfattning : The glutamate synapse is by far the most common synapse in the brain and acts via postsynaptic AMPA, NMDA and mGlu receptors. During brain development there is a continuous production of these synapses where those partaking in activity resulting in neuronal activity are subsequently selected to establish an appropriate functional pattern of synaptic connectivity while those that do not are elimimated. LÄS MER

  2. 2. Plasticity of the developing glutamate synapse in the hippocampus

    Detta är en avhandling från Göteborg : Göteborg University

    Författare :Therése Abrahamsson; Göteborgs universitet.; Gothenburg University.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; synaptic plasticity; long-term potentiation; short-term potentiation; silent synapse; development; hippocampus; glutamate;

    Sammanfattning : Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. LÄS MER

  3. 3. Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Jonas Thelin; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long term-potentiation; Cell adhesion molecule; Pain; Somatosensory imprinting; Medicin människa och djur ; Medicine human and vertebrates ; Nociceptive withdrawal reflex; Species differences; Central sensitisation; Mouse strains; Spinal cord;

    Sammanfattning : Popular Abstract in Swedish Medan akut smärta ofta kan bemästras på ett framgångsrikt sätt saknas ofta adekvat behandling av kroniska smärttillstånd. Smärta är ett dominerande symptom vid en mängd sjukdomar såsom till exempel, reumatoid artrit, cancer, migrän, ryggskador, fibromyalgi och tillgängliga analgetika är ofta otillräckliga. LÄS MER

  4. 4. Short- and long-term neuronal plasticity in hippocampal CA1 region of rat

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Fen-Sheng Huang; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glutamate; hippocampus; plasticity; synapse; LTP; LTD; AMPA; NMDA;

    Sammanfattning : The brain is highly plastic, displaying both short- and long-term changes, resulting from developmental processes as well as learning and memory. Moreover, short-term plasticity such as paired pulse facilitation and depression (PPF, PPD) have long been used to monitor the presynaptic versus postsynaptic changes occurring during more lasting processes such as long-term potentiation and depression (LTP, LTD). LÄS MER

  5. 5. Roles of SNAP-25 isoforms in activity-dependent long-term synaptic plasticity

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery

    Författare :Muhammad Irfan; Karolinska Institutet.; Karolinska Institutet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : SNARE proteins, SNAP-25, syntaxin 1A and VAMP2 constitute the functional units which join together to form the core SNARE complex. The SNARE complex carries out the vital function of membrane fusion of intracellular vesicles with plasma membranes, leading to the release of neurotransmitters in brain neuronal circuits and of hormones in endocrine glands. LÄS MER