Avancerad sökning

Visar resultat 11 - 15 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. Reverse Transcriptase Activity Assays for Retrovirus Quantitation and Characterization

    Författare :Anders Malmsten; Ulf Gyllensten; Clas Källander; Lynn Morris; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; retrovirus; reverse transcriptase; enzyme activity assay; MuLV; HIV; RT purification; viral load; drug susceptibility; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of different retroviruses, particularly HIV. LÄS MER

  3. 12. HIV and pregnancy : an epidemiological, clinical and virological study of HIV-infected pregnant women and their offspring

    Författare :Susanne Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; pregnancy; screening; viraemia; CD4 cell counts; counselling; perinatal transmissionStockholm 1996;

    Sammanfattning : Background: HIV infection is spread throughout most parts of the world with a substantial risk for a fatal outcome within 10 years. The virus is transmitted sexually, by infected blood and from mother to child. Whether the course of am HIV infection in women is changed by pregnancy is not known. LÄS MER

  4. 13. HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations

    Författare :Willy Shileanga Kikoka Urassa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; antibody detection; alternative confirmatory strategy; lymphocyte subsets; Tanzania; Africa.;

    Sammanfattning : The objectives of the studies that are reported in this thesis were to evaluate HIV antibody testing strategies and prognostic markers and to study inummological deterioration of HIV-1 infected individuals. Alternative testing strategies for confirmation of HIV seropositivity were evaluated using combinations of screening assays. LÄS MER

  5. 14. A microcell hybrid based elimination test to identify human chromosome 3 regions that antagonize tumor growth

    Författare :Irina Kholodnyuk Holodnuka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Deletions at multiple sites on the short arm of chr3 have been detected in many different types of human tumors. Each of the deleted regions is expected to harbor a tumor antagonizing/suppressor gene(s) (TSG). The earlier studies showed that the tumorigenicity of malignant cells could be suppressed by introducing a single human chr3. LÄS MER

  7. 15. Enhancement of HIV-1 DNA immunogens

    Författare :Anne Kjerrström Zuber; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; DNA vaccination; regulatory genes; adjuvants; experimental HIV-1 model;

    Sammanfattning : Human immunodeficiency virus type 1 eludes control by the immune response through a high degree of variability and immune escape mechanisms. Induction of a broad specific immune response is important to clear virus-infected cells. LÄS MER