Sökning: "ortholog"

Visar resultat 21 - 25 av 44 avhandlingar innehållade ordet ortholog.

  1. 21. Evolution and Pharmacology of Neuropeptide Y Receptors, Implications for vertebrate genome duplications

    Författare :Robert Fredriksson; Susanne Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Evolution; tetraploidizations; G-protein coupled receptor; neuropeptide Y; zebrafish; chicken; rainbow trout; lamprey; genome duplications; peptide YY; pancreatic polypeptide; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The Y receptors comprise a family of evolutionarily related receptors belonging to the superfamily of G-protein coupled receptors (GPCR). Their natural ligands are in mammals neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER

  3. 22. Functional study of hemolymph coagulation in Drosophila larvae

    Författare :Zhi Wang; Ulrich Theopold; Brian Lazzaro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; innate immunity; hemolymph coagulation; clot components; Drosophila larvae; Molecular Biology; molekylärbiologi;

    Sammanfattning : Many pathogen infections in nature are accompanied by injury and subsequent coagulation. Despite the contribution of hemolymph coagulation to wound sealing, little is known about its immune function. LÄS MER

  4. 23. Chemokines and their role in dopaminergic development

    Författare :Linda C Edman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The main pathological hallmark in Parkinson s disease (PD) is the progressive loss of dopaminergic (DA) neurons in the substantia nigra (SN), affecting movements such as walking, talking and writing. Today, there is no cure available for PD and existing treatments only provide symptomatic relief, but the prospect of using stem cell based cell replacement therapies for patients with PD have provided new optimism. LÄS MER

  5. 24. Deciphering molecular mechanisms in the evolution of new functions

    Författare :Hind Abdalaal; Joakim Näsvall; Paul Rainey; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolvability; functional trade-offs; collateral toxicity; duplication and amplification; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : The evolution of new genes and functions is considered to be a major contributor to biological diversity in organisms. Through de novo origination, “duplication and divergence”, and horizontal gene transfer, organisms can acquire new genetic material that can evolve to perform novel functions. LÄS MER

  7. 25. Cold Acclimation : Dissecting the plant low temperature signaling pathway using functional genomics

    Författare :Catherine Benedict; Vaughan Hurry; Matsuo Uemura; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cold acclimation; functional genomics; microarray; Populus tremula; Arabidopsis thaliana; gene voting; regulon; enhancer-blocking; Plant physiology; Växtfysiologi;

    Sammanfattning : The physiological process of cold acclimation protects plants native to the temperate regions of the world from the deleterious effects of low and freezing temperatures. This is achieved by a series of transcriptional, regulatory, and metabolic changes that enable continued growth and survival. Within minutes of exposure to temperatures below ca. LÄS MER