Sökning: "neutrophils"

Visar resultat 31 - 35 av 403 avhandlingar innehållade ordet neutrophils.

1. 31. Interleukin-17 in models of neutrophilic lung disease

   Författare :Stefan Ivanov; Göteborgs universitet; []
   Nyckelord :Interleukin-17; Interleukin-23; Matrix metalloproteinase-9; neutrophils; macrophages; CD4 cells; innate response; lungs;

   Sammanfattning : Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs of an excess innate response in the bronchoalveolar space. Neutrophils may play a pathogenic role in these lung diseases by contributing to non-specific bronchial hyperresponsiveness and bronchial hypersecretion, as well as to epithelial damage and tissue remodelling. LÄS MER

3. 32. Interleukin-17 in non-allergic airway inflammation

   Författare :Martti Laan; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

   Sammanfattning : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. LÄS MER

4. 33. Toll-like Receptors in Allergic Rhinitis

   Författare :Mattias Fransson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; poly I:C ; uteroglobin; Toll-like receptors; Medicine human and vertebrates ; Medicin människa och djur ; Otorhinolaryngology; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; innate immunity; LPS; allergic rhinitis; bone marrow;

   Sammanfattning : Allergic rhinitis is an inflammatory disorder with the characteristic symptoms itching, sneezing, secretion and blockage upon allergen contact. In addition to the local inflammation in the nose, there is a systemic component that influences peripheral blood, bone marrow and lungs. LÄS MER

5. 34. Chemoattractant receptor signaling and neutrophil acctivation. Involvement of the cytoskeleton

   Författare :Huamei Fu; Göteborgs universitet; []
   Nyckelord :neutrophils; G-protein coupled receptors; signaling; cytoskeleton;

   Sammanfattning : Neutrophil granulocytes play a vital role in the host surveillance system and form the first line of defense against microbial infections. The migration of neutrophils to an infected/inflamed tissue is guided by chemoattractants released either from intruding microbes or from activated/damaged host cells. LÄS MER

7. 35. Regulation of human eosinophil transmigration across lung epithelium

   Författare :Lixin Liu; Uppsala universitet; []
   Nyckelord :Medical sciences; Eosinophils; regulation; migration; epithelial cells; lung; calcium; CD11b CD18; neutrophils; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. LÄS MER