Sökning: "CD11b CD18"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden CD11b CD18.

  1. 1. Regulation of human eosinophil transmigration across lung epithelium

    Författare :Lixin Liu; Uppsala universitet; []
    Nyckelord :Medical sciences; Eosinophils; regulation; migration; epithelial cells; lung; calcium; CD11b CD18; neutrophils; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. LÄS MER

  2. 2. Leukocyte dysfunction and inflammatory markers in patients with chronic kidney disease and patients on dialysis

    Författare :Jenny Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Patients with chronic kidney disease (CKD) and patients on dialysis are at risk for serious infectious complications. This is partly due to leukocyte dysfunction, which is a consequence of both uremic retention solutes and of dialysis. LÄS MER

  3. 3. Interactions between Streptococcus pyogenes and the Human Immune System

    Författare :Maria Weineisen; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; virologi; mykologi; Immunology; mycology; Mikrobiologi; bakteriologi; virology; Biomedicinska vetenskaper; Neutrophils; Streptococcus pyogenes; Biomedical sciences; Phagocytosis; bacteriology; Microbiology; Integrins;

    Sammanfattning : Streptococcus pyogenes is a common human pathogen causing mild infections such as tonsillitis and pharyngitis, but is also the cause of life-threatening conditions. To be able to infect the human host, S. pyogenes express different virulence factors. The surface-expressed M protein is a major virulence factor of S. LÄS MER

  4. 4. Modulation of adhesion molecules on leukocytes during clinical and experimental hemodialysis : endothelial cell interacions

    Författare :Pia Thylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Adhesion; adhesion molecules; complement; endothelial cells; hemodialysis; integrins; interleukin; leukocytes; selectins.;

    Sammanfattning : Modulation of adhesion molecules on leukocytes during clinical and experimental hemodialysis - endothelial cell interactions Pia ThylenIn patients on hemodialysis the sequential steps required for adhesion molecule mediated ad-herence of leukocytes to endothelial cells are unphysiologically disrupted since cell activationwith subsequent alterations in adhesion molecule phenotypes takes place in the extracorporealcircuit far away from the respective endothelial cell ligand.The aims of the present investigations were to study the changes in adhesion molecule phenotypeson inflammatory cells induced by clinical and experimental hemodialysis and the consequenceswith regard to the capacity of the cells to adhere to endothelial cells. LÄS MER

  5. 5. The biological mechanisms in neutrophil and eosinophil adhesion and transmigration in vitro and theur relation to the inflammatory process in vivo

    Författare :Ali Moshfegh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : In inflammatory reactions, eosinophils and neutrophils constitute the major classes of granulocytes that emigrate from the bloodstream into the tissues. The recruitment of inflammatory cells constitutes a multi-step process that includes sequential adhesion and transmigration through, the endothelial lining, the underlying basement membrane and a variety of extracellular matrix components. LÄS MER