Sökning: "neuron survival"

Visar resultat 21 - 25 av 78 avhandlingar innehållade orden neuron survival.

  1. 21. Identification of pathways of degeneration and protection in motor neuron diseases

    Författare :Susanne Nichterwitz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Motor neuron diseases preferentially affect specific neuronal populations with distinct clinical features even if disease-causing genes are expressed in many cell types. In spinal muscular atrophy (SMA), somatic motor neurons are selectively vulnerable to a deficiency in the broadly expressed survival of motor neuron 1 (SMN1) gene. LÄS MER

  2. 22. Olfactory mechanisms of host selection in phytophagous insects : behavior, neuron, and receptor

    Författare :Muhammad Binyameen; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The most challenging tasks for phytophagous insects are the location and selection of mates, food sources, and oviposition sites, all crucial for survival and reproduction. To perform these tasks insects rely largely on their sense of smell (olfaction). LÄS MER

  3. 23. On the occurrence and possible causes of motor neuron disease in Sweden

    Författare :Lars-Gunnar Gunnarsson; Linköpings universitet; []
    Nyckelord :Epidemiology; amyotrophic lateral sclerosis; incidence; prevalence; mortality; cluster; Iisk factors; occupation; environment; agricultural work; electrical work; welding; solvents; heredity; MEDICINE; MEDICIN;

    Sammanfattning : A series of investigations have been performed to study secular trends of motor neuron disease (MND) morbidity and mortality in Sweden, to identify time and/or space clusters, if any, and to uncover risk factors. The occurrence of the disease was estimated from incidence, prevalence and mortality rates, and the strength of various determinants was evaluated by means of the case-control approach, using population controls. LÄS MER

  4. 24. Death, survival, and morphological development of hippocampal granule cells born in an inflammatory environment

    Författare :Sara Bonde; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microglia; hippocampus; Adult neurogenesis; gephyrin; dendritic spines;

    Sammanfattning : The brain continues to form new neurons throughout life. This process of adult neurogenesis has been thoroughly documented in several species including birds, rodents and humans. LÄS MER

  5. 25. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada : clinical, neurophysiological and neuropathological features

    Författare :Heather G. Stewart; Hiroshi Mitsumoto; Umeå universitet; []
    Nyckelord :ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. LÄS MER