Sökning: "dendritic spines"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden dendritic spines.

  1. 1. Endoplasmic reticulum function in dendrites and dendritic spines of hippocampal neurons

    Författare :Ai Na Ng; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoplasmic reticulum; primary culture; dendritic spines; live cell imaging; STIM1; carbachol; store-operated calcium entry; 3; familial Alzheimer s disease; 5-dihyroxyphenyglycine;

    Sammanfattning : In the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. LÄS MER

  3. 2. Death, survival, and morphological development of hippocampal granule cells born in an inflammatory environment

    Författare :Sara Bonde; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microglia; hippocampus; Adult neurogenesis; gephyrin; dendritic spines;

    Sammanfattning : The brain continues to form new neurons throughout life. This process of adult neurogenesis has been thoroughly documented in several species including birds, rodents and humans. LÄS MER

  4. 3. The paralemmin protein family : Phosphoproteins involved in filopodia and dendritic spine formation

    Författare :Nicole G. Neumann; Klas Kullander; Karin Nordström; Eirc Hanse; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : Dendritic spines, which connect neurons with each other, constitute most of the excitatory synapses and undergo experience-dependent neuronal plasticity. The function of dendritic spines and their synaptic strength are highly correlated with morphological changes. LÄS MER

  5. 4. Plasticity in the dopamine 1 receptor system : behavior and cell biological studies

    Författare :Lena Scott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasticity; dopamine; D1R; NMDA; motor activity; spines;

    Sammanfattning : Dopamine is a key neurotransmitter in the brain, and has an important modulatory role in the control of motor activity and cognitive processes. Dysfunctions of the dopamine system have been implicated in several neuropsychiatric disorders such as schizophrenia and attention-deficit/hyperactivity disorder. LÄS MER

  7. 5. Mathematical Models in Cellular Biophysics

    Författare :Jacob Kowalewski; Hjalmar Brismar; Erik Fransén; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Calcium oscillations; Diffusion; Dopamine receptors; Mathematical models; Computer simulations; FRAP; Physics; Fysik;

    Sammanfattning : Cellular biophysics deals with, among other things, transport processes within cells. This thesis presents two studies where mathematical models have been used to explain how two of these processes occur. Cellular membranes separate cells from their exterior environment and also divide a cell into several subcellular regions. LÄS MER