Sökning: "Malin Grönberg"

Hittade 2 avhandlingar innehållade orden Malin Grönberg.

  1. 1. Expression of Neuroendocrine Markers in Normal and Neoplastic Tissue with an Emphasis on Ghrelin and Obestatin

    Författare :Malin Grönberg; Eva Tiensuu Janson; Apostolos Tsolakis; Jan Saras; Mauro Papotti; Uppsala universitet; []
    Nyckelord :ghrelin; obestatin; neuroendocrine marker; immunohistochemistry; neuroendocrine tumors; breast cancer; mammary glands; MEDICINE; MEDICIN; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : The aim of this thesis was to characterize the expression of the peptides ghrelin and obestatin, as well as other neuroendocrine markers in human normal tissues, in invasive breast cancer and a wide panel of neuroendocrine tumors (NETs). In normal tissues the expression of ghrelin and obestatin was mainly localized to the gastric mucosa, and in lesser extent in the remaining gastrointestinal tract, endocrine pancreas and mammary glands. LÄS MER

  2. 2. Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 : Biological and Clinical Aspects

    Författare :Abir Salwa Ali; Malin Grönberg; Christoffer Juhlin; Uppsala universitet; []

    Sammanfattning : The aim of this thesis was to investigate biological and clinical aspects of G3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs).In our first study, the expression of the tumor suppressor p53 was investigated. In a cohort of G3 GEP-NENs we found the expression of p53 protein to be present in 39% of 124 cases. LÄS MER