Sökning: "Endocrine pancreatic tumour"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Endocrine pancreatic tumour.

  1. 1. Pancreatic Endocrine Tumourigenesis Genes of potential importance

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Térèse A. Johansson; Uppsala universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic endocrine tumour; Multiple endocrine neoplasia type 1; Tumourigenesis; Notch signalling; Notch1; Hes1; Neurog3; Neurod1; Men1; Ascl1; Pou3f4; Pdx1; Rpl10; Dlk1; Dkk1; Tph1; menin; MEDICINE Morphology; cell biology; pathology Morphology Tumour biology; MEDICIN Morfologi; cellbiologi; patologi Morfologi Tumörbiologi;

    Sammanfattning : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. LÄS MER

  2. 2. Somatostatin Receptor Expression and Biological Functions in Endocrine Pancreatic Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Eva Ludvigsen; Uppsala universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; somatostatin; somatostatin receptors; somatostatin analogues; NOD mouse; type 1 diabetes; pancreatic islets; BON-1 cells; Cellbiologi; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi;

    Sammanfattning : Type 1 diabetes is resulting from the selective destruction of insulin-producing beta-cells within the pancreatic islets. Somatostatin acts as an inhibitor of hormone secretion through specific receptors (sst1-5). LÄS MER

  3. 3. Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christina Swärd; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carcinoid; Endocrine pancreatic tumour; Neuroendocrine; Octreotide; Somatostatin receptor; Peptide receptor; Radionuclide therapy; Absorbed dose; Chromogranin A; Liver transplantation;

    Sammanfattning : Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. LÄS MER

  4. 4. Hypoxia-inducible factor-1 (HIF-1) in pancreatic cancer cell aggressiveness and therapeutic resistance and the potential role for pancreatic endocrine cells in islet transplantation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Författare :Xiaohui Jia; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tissue hypoxia results from an inadequate supply of oxygen (O2) that compromises biologic functions in various tissues, including both normal and malignant. It is known that a heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1) mainly mediates this critical adaptation. LÄS MER

  5. 5. High-molecular-weight insulin-like growth factor 2 : Immunohistochemical, ultrastructural and biochemical findings in insulin cells under normal, diabetic, and neoplastic conditions, and its role in non-islet-cell-tumour hypoglycaemia

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Anders Höög; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin-like growth factor-2; IGF-2; islets of Langerhans; B-granules; Diabetes Mellitus type 2; insulinoma; Goto-Kakizaki rat; haemangiopericytoma; ultrastructural immunohistochemistry; gene expression.;

    Sammanfattning : High-Molecular-Weight Insulin-Like Growth Factor 2 Immunohistochemical, Ultrastructural, and Biochemical Findings in Insulin Cells under Normal, Diabetic, and Neoplastic Conditions, and Its Role in Non-lslet-Cell-Tumour Hypoglycaemia by Anders Höög Department of Oncology and Pathology, Unit of Tumour Pathology, Karolinska Institute and Hospital, Stockholm, Sweden. IGF-2 immunoreactive (IR) cells were identified in the normal adult pancreas of man and rat and occurred exclusively in insulin-producing cells. LÄS MER