Sökning: "Peptide receptor"

Visar resultat 1 - 5 av 440 avhandlingar innehållade orden Peptide receptor.

  1. 1. Galanin receptor ligands

    Detta är en avhandling från Stockholm : Department of Neurochemistry, Stockholm University

    Författare :Johan Runesson; Stockholms universitet.; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; neurokemi med molekylär neurobiologi; Neurochemistry and Molecular Neurobiology;

    Sammanfattning : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. LÄS MER

  2. 2. Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule Peptide Conjugates as Protein Actors

    Detta är en avhandling från Institutionen för fysik, kemi och biologi

    Författare :Jonas Nilsson; Linköpings universitet.; Linköpings universitet.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Synthetic receptor; Peptide inhibitor conjugate; Peptide protein surface interactions; General Lead Discovery Library; Combinatorial Chemistry; Solid Phase Chemistry; Targeted Library; Thrombin inhibitor; Fluorescence; Surface Plasmon Resonance; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Sammanfattning : This thesis describes different aspects of protein interactions. Initially the function of peptides and their conjugates with small molecule inhibitors on the surface of Human Carbonic Anhydrase isoenzyme II (HCAII) is evaluated. LÄS MER

  3. 3. Combinatorial Methodology. Screening for affinity specific ligands to biological and artificial receptors

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Margareta Krook; Lunds universitet.; Lund University.; [1998]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptide library; combinatorial; screening; phage display; affinity; DNA-interaction; chymotrypsin; peptide inhibitor; antibody; IgG; Fc; molecular imprinting; steroid; receptor; Biochemistry; Metabolism; Biokemi; Biotechnology; Bioteknik;

    Sammanfattning : Combinatorial screening methodology has been employed to select new affinity specific ligands to bilogical and artificial receptors. The screening methodology, in particular screening of combinatorial phage display peptide libraries against target molecules differing in function and shape, is focused upon. LÄS MER

  4. 4. Activation of professional phagocytes with emphasis on the formyl peptide receptor family

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Jennie Karlsson; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phagocyte; G-protein coupled receptor; chemoattractant; formyl peptide receptor; reactive oxygen species; calcium;

    Sammanfattning : Phagocytic cells such as neutrophil granulocytes and monocytes are an essential part of our innate immune system and play an important role in the battle against pathogens. G-protein coupled receptors (GPCRs) and more specifically chemoattractant receptors are a vital part in guiding phagocytes towards the site of infection. LÄS MER

  5. 5. Galanin receptor ligands : Design, synthesis, characterization and biological effects

    Detta är en avhandling från Stockholm : Department of Neurochemistry

    Författare :Kristin Webling; Stockholms universitet.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. LÄS MER