Sökning: "natural antibodies"

Visar resultat 31 - 35 av 352 avhandlingar innehållade orden natural antibodies.

  1. 31. IgE sensitization against food allergens : Natural history, relation to airway inflammation and asthma

    Författare :Antonios Patelis; Andrei Malinovschi; Eva Rönmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergen components; extract-based; exhaled NO; airway hyperresponsiveness; blood eosinophil count; IgE sensitization; food hypersensitivity; food allergens; perennial allergens; natural history; markers of systemic inflammation; markers of local inflammation; Lungmedicin; Lung Medicine; Fysiologi; Physiology; Immunologi; Immunology;

    Sammanfattning : Background: According to recent studies in children, IgE sensitization not only against perennial allergens, but also against food allergens, is related to asthma risk and increased airway inflammation. During the last decade, a new technique for IgE determination based on allergen components has become available, but its use in epidemiological studies has been limited. LÄS MER

  3. 32. Immunological characteristics of recombinant fragments of the Plasmodium falciparum blood-stage antigen Pf332

    Författare :Halima A. Balogun; Klavs Berzins; Lars Hviid; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasmodium falciparum; Pf332; antibodies; immunity; growth inhibition; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Effective malaria vaccine might help improve control strategies against malaria, but the complexity of interactions between the parasite and its hosts poses challenges. The asexual blood stage P. falciparum antigen Pf332 has potentials as one of the proteins in understanding the complex host-parasite interactions. LÄS MER

  4. 33. Phenotypic antibody discovery and mining of complex antibody libraries

    Författare :Anne Ljungars; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibody discovery; Phage display; Phenotypic screening; Cell selection; Deep mining; Complex phage pools;

    Sammanfattning : Therapeutic antibodies are the fastest growing class of drugs but suffer from a crowded target-space where many antibodies, against a few targets, are developed in parallel. The aim of this thesis is to find methods to enable discovery of novel antibody-target combinations and thereby increase the target-space. LÄS MER

  5. 34. Engineering of small IgG binding domains for antibody labelling and purification

    Författare :Sara Kanje; Sophia Hober; Cecília Roque; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody; labelling; purification; Protein G; Protein A; protein engineering; protein design; combinatorial selection; Bioteknologi; Biotechnology;

    Sammanfattning : In protein engineering, rational design and selection from combinatorial libraries are methods used to develop proteins with new or improved features. A very important protein for the biological sciences is the antibody that is used as a detecting agent in numerous laboratory assays. LÄS MER

  7. 35. Malarial anaemia : the potential involvement of Plasmodium falciparum rhoptry proteins

    Författare :Nancy Awah; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Malaria remains a challenging health problem in malaria endemic regions. Infection with malaria invariably leads to anaemia. The groups at risk of developing malarial anaemia include children below the age of five years and pregnant women, especially primigravidae. LÄS MER