Sökning: "Complex phage pools"

Hittade 1 avhandling innehållade orden Complex phage pools.

1. 1. Phenotypic antibody discovery and mining of complex antibody libraries

   Författare :Anne Ljungars; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibody discovery; Phage display; Phenotypic screening; Cell selection; Deep mining; Complex phage pools;

   Sammanfattning : Therapeutic antibodies are the fastest growing class of drugs but suffer from a crowded target-space where many antibodies, against a few targets, are developed in parallel. The aim of this thesis is to find methods to enable discovery of novel antibody-target combinations and thereby increase the target-space. LÄS MER