Sökning: "natural antibodies"
Visar resultat 21 - 25 av 352 avhandlingar innehållade orden natural antibodies.
21. Modulation of B cell access to antigen by passively administered antibodies : an explanation for antibody feedback regulation?
Sammanfattning : Antibody responses can be up- or down-regulated by passive administration of specific antibody together with antigen. Depending on the structure of the antigen and the antibody isotype, responses can be completely suppressed or enhanced up to a 1000-fold of what is seen in animals immunized with antigen alone. LÄS MER
22. Monoclonal antibodies against carcinoembryonic antigen and their use in tumor diagnosis
Sammanfattning : A new CEA-related substance, (CEAlow) was isolated from liver metastases of colorectal cancer. Purified CEAlow was homogeneous by several physico-chemical criteria. It had an apparent molecular weight of 125,000. 2/9 monkey anti-CEA sera gave a spur with CEA over CEAlow in immunodiffusion. LÄS MER
23. Surface Properties of Antibodies and their Complexes with Antigens Studied by LLPC
Sammanfattning : The main objective of this thesis was to gain further insight into the relationship between the exposed surfaces and the functional properties of antibodies and their complexes with antigens in solution. To study this relationship, a new technique, liquid-liquid partition chromatography (LLPC) in aqueous two-phase systems, was developed further with respect to sensitivity, selectivity and reproducibility. LÄS MER
24. Antigen processing and presentation by B lymphocytes decorated with passively incorporated antibodies
Sammanfattning : .... LÄS MER
25. Development and evaluation of analytical techniques for antibodies and antibody-drug conjugates : From verification of conjugation to stability testing
Sammanfattning : Antibody-drug conjugates (ADCs) are becoming increasingly important in oncology. ADCs are inherently heterogeneous analytes. For a successful drug candidate to go through to the clinic, extensive characterization and evaluation of the constructs are necessary. LÄS MER