Sökning: "airway hyperresponsiveness"
Visar resultat 1 - 5 av 34 avhandlingar innehållade orden airway hyperresponsiveness.
1. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma
Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER
2. Airway responsiveness and exhaled nitric oxide : Studies in asthma and Sjögren's syndrome
Sammanfattning : In this thesis, four different types of provocation agents: methacholine, adenosine, cold air and mannitol were used to study different aspects of the airway responsiveness profile in asthma and Sjögren's syndrome. Exhaled nitric oxide (NO) and markers of eosinophil activation, serum eosinophil peroxidase (S-EPO) and eosinophil cationic protein (S-ECP) were measured. LÄS MER
3. IgE sensitization against food allergens : Natural history, relation to airway inflammation and asthma
Sammanfattning : Background: According to recent studies in children, IgE sensitization not only against perennial allergens, but also against food allergens, is related to asthma risk and increased airway inflammation. During the last decade, a new technique for IgE determination based on allergen components has become available, but its use in epidemiological studies has been limited. LÄS MER
4. From sneeze to wheeze: Non-invasive studies on asthma and rhinitis
Sammanfattning : Asthma and allergic rhinitis are diseases that cause major disability and illness in all ethnic groups and ages. It is well established that allergic rhinitis and asthma are closely linked entities and more than 75 % of the patients with asthma reports concomitant rhinitis. LÄS MER
5. Airway effects of diesel exhaust in healthy and asthmatic subjects
Sammanfattning : Several epidemiological studies have revealed an association between particulate matter (PM) pollution and various health effects. Importantly, there is evidence to suggest that individuals with pre-existing respiratory disease, such as asthma, are more sensitive to elevated ground levels of particulate matter as compared to healthy subjects. LÄS MER