Sökning: "myocyte"

Visar resultat 6 - 10 av 16 avhandlingar innehållade ordet myocyte.

  1. 6. Cardiomyocyte Cell Cycle, Renewal and Isolation

    Författare :Stuart Walsh; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; binucleation; Cardiomyocytes; surface marker; troponin-T; mitosis; microarray; cell cycle; FACS;

    Sammanfattning : Heart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. LÄS MER

  3. 7. Energy-Related Metabolites during and after Induced Myocardial Ischemia and Retroperfusion of the Coronary Sinus : An Experimental Study in the Pig with the Microdialysis Technique and Extracorporeal Circulation

    Författare :Vitas Zemgulis; Rolf Ekroth; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Ischemia; myocardial infarction; reperfusion; energy metabolism; coronary sinus retroperfusion; microdialysis; taurine; nucleoside transport; adenosine; aerobic lactate production; Kirurgi; Surgery; Kirurgi; Thoracic and Cardivascular Suregery; kirurgi; särskilt thoraxkirurgi;

    Sammanfattning : In the clinical setting great efforts have been made with contradictory results to operate upon acutely myocardial ischemic patients. The reasons for the absence of unambiguous results are not well understood nor are they scientifically explored. LÄS MER

  4. 8. Release and Clearance Mechanisms of Cardiac Troponin

    Författare :Karin Starnberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; cardiac; Troponin;

    Sammanfattning : Myocardial infarction (MI) is often suspected when a patient presents with chest pain. MI is defined as cardiac necrosis due to ischemia, most often mediated through impaired coronary perfusion. Cardiac necrosis results in the release of myoglobin, creatine kinase and cardiac troponin (cTn) to the circulation. LÄS MER

  5. 9. Genetic and pathophysiological study of desmin derangements in cardiac disorders

    Författare :Anna Kostareva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Desmin is a chief intermediate filament of skeletal and cardiac muscle. Its main function is to provide structural and functional integrity to the cell and to transmit tension along the myofibrils, protecting them from mechanical stress during contractionrelaxation process. LÄS MER

  7. 10. ß-Adrenergic receptor gene polymorphism in dilated cardiomyopathy. Clinical and functional relevance

    Författare :Malin Levin; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : During normal physiological conditions, catecholamines induce positive inotropic and chronotropic responses in the heart through a ß-adrenergic receptor (AR)-activated pathway. The agonist-bound ßAR selectively interacts with the stimulatory Gs-protein, which activates adenylyl cyclase, catalyzing cAMP formation. LÄS MER