Sökning: "surface marker"
Visar resultat 1 - 5 av 136 avhandlingar innehållade orden surface marker.
1. Towards specific quantification of exosomes using surface-based sensing
Sammanfattning : When exosomes were first observed in 1967, they were believed to be cell debris until extensive studies demonstrated key biological functionalities related to their composition and formation mechanism. Exosomes are nanometer-sized lipid vesicles of endocytic origin, with a membrane consisting of lipids and proteins and encapsulating a cargo composed of soluble proteins and genetic material. LÄS MER
2. Physical characterization of exosomes and other extracellular vesicles using surface-based sensing
Sammanfattning : Extracellular vesicles (EVs) are hundred of nanometer sized particles secreted by almost all cell types. Exosomes are one type of EVs today intensively investigated due to the increased evidence suggesting that they play important roles as communicating vehicles in a broad range of physiological processes, pathological conditions and disease diagnostics. LÄS MER
3. Microfluidics in Surface Modified PDMS : Towards Miniaturized Diagnostic Tools
Sammanfattning : There is a strong trend in fabricating miniaturized total analytical systems, µTAS, for various biochemical and cell biology applications. These miniaturized systems could e.g. gain better separation performances, be faster, consume less expensive reagents and be used for studies that are difficult to access in the macro world. LÄS MER
4. Cardiomyocyte Cell Cycle, Renewal and Isolation
Sammanfattning : Heart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. LÄS MER
5. On osseointegration in response to controlled surface nanotopography
Sammanfattning : Knowledge about the biological responses provoked by the surface modification of titanium implants on the nanoscale is still in its infancy. Although in vitro studies claim superior effects considering higher adhesion and proliferation of osteoblasts in the short term and even differentiation towards the osteogenic cell lineage in the long term, these responses do not necessarily reflect the actual outcome in the complex in vivo environment. LÄS MER