Sökning: "mucosal host response"

Visar resultat 26 - 30 av 58 avhandlingar innehållade orden mucosal host response.

  1. 26. Characterization of surface components of Moraxella catarrhalis and pathogenic Neisseria

    Författare :Motiur Rahman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Moraxella catarrhalisantibody LPS NeisseriapiliPilC;

    Sammanfattning : Infection is a multistep process including adhesion, colonisation, invasion and multiplication which finally results in disease. Bacterial surface components and virulence factors are essential for all these different steps and they are co-ordinately regulated during the different steps of pathogenesis and infection. LÄS MER

  3. 27. Effects of bacterial genotoxins on immune modulation, chronic inflammation and cancer development

    Författare :Anna Bergonzini; Teresa Frisan; Maria Fällman; Steffen Backert; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologi; Immunology;

    Sammanfattning : The intestinal microbiome of Inflammatory Bowel Disease and colorectal cancer patients is enriched in genotoxin-producing bacteria, which cause DNA damage in the host cells.Genotoxins have recently been identified as a novel family of effectors produced by pathogenic and commensal bacteria. LÄS MER

  4. 28. Intestinal Mucosa Reconstitution and Protection: Impact of Luminal Factors

    Författare :Yilei Mao; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Probiotics; Pectin; Oat; Methotrexate; Lactobacilli; Intestinal injury; Intestinal immunity; Intestinal barrier; Enterocolitis; Fiber; Radiation; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : The gastrointestinal mucosa is one of the most rapidly proliferating tissues in the body, and serves as a barrier to luminal bacteria and toxins. Enteral nutrition, luminal fiber and probiotics are of crucial importance for the integrity of this barrier. LÄS MER

  5. 29. Citrobacter rodentium and Escherichia coli interactions with mucus producing colonic epithelical cells

    Författare :Sinan Sharba; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; A E pathogens; cytokines; epithelium; mitochondria; mucus;

    Sammanfattning : The epithelial cells together with the mucus layer protect the host from noxious luminal substances and pathogenic invasion. Pathogens have evolved numerous strategies to circumvent these barriers and mount infection. C. rodentium is a murine model for the attaching and effacing intestinal E. LÄS MER

  7. 30. Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression

    Författare :Emma C Skoog; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; Lactobacillus; adhesion; proliferation; gene expression; CagA; SabA; BabA; ArsS; Fur;

    Sammanfattning : Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily glycosylated mucins that build up the mucus layer. The carbohydrate structures on the mucins that act as ligands for H. LÄS MER