Sökning: "mucosal host response"
Visar resultat 16 - 20 av 58 avhandlingar innehållade orden mucosal host response.
16. Helicobacter pylori interference with the L-arginine/NO pathway in the upper gut
Sammanfattning : Helicobacter pylori causes chronic gastritis and sometimes peptic ulcers but the pathogenesis is not fully understood. H. pylori-infected individuals with duodenal ulcer have an impaired duodenal mucosal bicarbonate secretion (DMBS) in response to acid. NO is an important signalling molecule in the body. LÄS MER
17. Tear Secretory IgA: A Noninvasive Biomarker of Mucosal Immune Competence
Sammanfattning : Since early studies investigated the influence of exercise on salivary secretory IgA(SIgA) in the 1980s, there has been demand for non-invasive biomarkers capableof monitoring the immune response to exercise, training and stress, and provideinsight into whether such stressors may influence susceptibility to URTI. In spiteof >30 years of research and ~200 original articles investigating a multitude ofcandidate markers, this tool remains elusive. LÄS MER
18. Regulation of gut IgA induction by helper T cells
Sammanfattning : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. LÄS MER
19. Influence of host genetics on innate immunity and susceptibility to urinary tract infection
Sammanfattning : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. LÄS MER
20. The development of a new combined adjuvant vector for mucosal immunization CTA1-DD/ISCOM
Sammanfattning : The CTA1-DD/ISCOMs vector is a rationally designed mucosal adjuvant that was developed to host the distinctive properties of either adjuvant alone or in a combination that hosted additive enhancing effects on mucosal immune responses. Here I demonstrate that CTA1-DD can be incorporated into the ISCOM with greatly augmented immunogenicity of both incorporated and admixed antigen. LÄS MER